[PDF][PDF] SEB-induced IL-13 production in CLA+ memory T cells defines Th2 high and Th2 low responders in atopic dermatitis

L Sans-De San Nicolàs, I Figueras-Nart, M Bonfill-Ortí… - 2022 - repositori.upf.edu
To the Editor, Staphylococcus aureus, memory skin-homing cutaneous
lymphocyteassociated antigen (CLA)+ T cells and IL-13 constitute relevant players in atopic …

Interaction of allergens, major histocompatibility complex molecules, and T cell receptors: a 'menage a trois' that opens new avenues for therapeutic intervention in …

B Jahn-Schmid, WF Pickl, B Bohle - International archives of allergy and …, 2011 - karger.com
T cells are major players in the initiation and perpetuation of the allergic immune response.
In this review, we summarize the current knowledge on allergen recognition by T …

Temporal variation of Staphylococcus aureus clonal complexes in atopic dermatitis: a follow‐up study

ML Clausen, SM Edslev, LB Nørreslet… - British Journal of …, 2019 - academic.oup.com
Background A strong link between disease severity and Staphylococcus aureus colonization
of the skin has been reported in patients with atopic dermatitis (AD). Objectives To examine …

Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation

S Sehra, P Krishnamurthy, B Koh… - European journal of …, 2016 - Wiley Online Library
Atopic dermatitis (AD) is a chronic inflammatory skin disease induced by a complex
interaction between susceptibility genes encoding skin barrier components and …

T regulatory cells in atopic dermatitis and subversion of their activity by superantigens

LS Ou, E Goleva, C Hall, DYM Leung - Journal of Allergy and Clinical …, 2004 - Elsevier
BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease involving
colonization by superantigen (SAg)–secreting Staphylococcus aureus. CD4+ CD25+ T …

Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice

M Terada, H Tsutsui, Y Imai, K Yasuda… - Proceedings of the …, 2006 - National Acad Sciences
Atopic dermatitis (AD) is a common inflammatory skin disease of unknown etiology.
Cutaneous infection with microbes such as Staphylococcus aureus and/or skin cleansing …

Toll-like receptor 2 ligands promote chronic atopic dermatitis through IL-4–mediated suppression of IL-10

S Kaesler, T Volz, Y Skabytska, M Köberle… - Journal of Allergy and …, 2014 - Elsevier
Background Atopic dermatitis (AD) is a T cell–mediated inflammatory skin disease, with TH 2
cells initiating acute flares. This inflamed skin is immediately colonized with Staphylococcus …

[HTML][HTML] Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell …

E Laborel-Préneron, P Bianchi, F Boralevi, P Lehours… - PLoS …, 2015 - journals.plos.org
Interactions between the immune system and skin bacteria are of major importance in the
pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a …

[HTML][HTML] Regulation of T cell immunity in atopic dermatitis by microbes: the yin and yang of cutaneous inflammation

T Biedermann, Y Skabytska, S Kaesler… - Frontiers in …, 2015 - frontiersin.org
Atopic dermatitis (AD) is a chronic inflammatory skin disease predominantly mediated by T
helper cells. While numerous adaptive immune mechanisms in AD pathophysiology have …

Role of staphylococcal superantigens in atopic dermatitis: from colonization to inflammation

MO Taskapan, P Kumar - Annals of Allergy, Asthma & Immunology, 2000 - Elsevier
OBJECTIVE: This review article has been prepared in order to enable the readers to
understand the role of staphylococcal superantigens (SsAgs) in atopic dermatitis (AD) …