Exploring the Role of Staphylococcus Aureus Toxins in Atopic Dermatitis

F Seiti Yamada Yoshikawa, J Feitosa De Lima… - Toxins, 2019 - mdpi.com
Atopic dermatitis (AD) is a chronic and inflammatory skin disease with intense pruritus and
xerosis. AD pathogenesis is multifactorial, involving genetic, environmental, and …

Bacterial and viral infections in atopic dermatitis: a comprehensive review

PY Ong, DYM Leung - Clinical reviews in allergy & immunology, 2016 - Springer
Atopic dermatitis (AD) is the most common allergic skin disease in the general population. It
is a chronic inflammatory skin disease complicated by recurrent bacterial and viral infections …

Staphylococcus aureus‐derived membrane vesicles exacerbate skin inflammation in atopic dermatitis

SH Jun, JH Lee, SI Kim, CW Choi… - Clinical & …, 2017 - Wiley Online Library
Background Skin colonization or infection with Staphylococcus aureus is known to trigger
aggravation of atopic dermatitis (AD). However, the exact mechanisms by which S. aureus …

Scavenger receptor-specific allergen delivery elicits IFN-γ-dominated immunity and directs established TH2-dominated responses to a nonallergic phenotype

S Bhatia, S Mukhopadhyay, E Jarman, G Hall… - Journal of allergy and …, 2002 - Elsevier
Background: Immunotherapeutic approaches to allergy consist of reliably changing allergen-
specific TH2 immunity associated with secretion of IL-4, IL-5, and IL-13, along with IgE …

Augmentation of regulatory T cells in allergic individuals by recombinant Der f 2 peptide with fungal immunomodulatory peptide fve

CC Wu, EC Liao, MF Lee, JJ Tsai - Annals of Allergy, Asthma & Immunology, 2009 - Elsevier
BACKGROUND: The suppressive function of regulatory T (Treg) cells is compromised in
allergic individuals, and the augmentation of Treg cells has been demonstrated after …

Comparative immunophenotyping of monocytes from symptomatic and asymptomatic atopic individuals

D Von Bubnoff, M Scheler, T Hinz, H Matz, S Koch… - Allergy, 2004 - Wiley Online Library
Background: Allergy has at least two components–a genetic predisposition referred to as
atopy and the progress from an atopic state to clinically apparent disease. Peripheral blood …

New insights into T cells and their signature cytokines in atopic dermatitis

A Wang, N Xu Landén - IUBMB life, 2015 - Wiley Online Library
An imbalance of the adaptive immune system mediated by various T cells plays a pivotal
role in the pathogenesis of atopic dermatitis (AD). Traditionally, sustained exposure of …

Changes in markers associated with dendritic cells driving the differentiation of either TH2 cells or regulatory T cells correlate with clinical benefit during allergen …

C Gueguen, J Bouley, H Moussu, S Luce… - Journal of Allergy and …, 2016 - Elsevier
Background Regulatory dendritic cell (DC) markers, such as C1Q, are upregulated in
PBMCs of patients with grass pollen allergy exhibiting clinical benefit during allergen …

[HTML][HTML] Atopic dermatitis: Is innate or adaptive immunity in control? A clinical perspective

PY Ong - Frontiers in Immunology, 2022 - frontiersin.org
Atopic dermatitis (AD) is a chronic inflammatory skin disease with barrier defects and
immune dysregulations. The pathogenesis of AD involves the physical barrier as well as …

Mechanism of HBD-3 deficiency in atopic dermatitis

MD Howell, M Boguniewicz, S Pastore, N Novak… - Clinical …, 2006 - Elsevier
Extrinsic atopic dermatitis (EAD) and intrinsic atopic dermatitis (IAD) patients suffer from
recurrent bacterial and viral infections. In this study, we demonstrate significantly decreased …