Chrysin ameliorates STZ-induced diabetes in rats: possible impact of modulation of TLR4/NF-κβ pathway
Background and purpose: Growing evidence advocates that upregulation of toll-like receptor
4 (TLR4) has been suggested as a causative influence in the development and …
4 (TLR4) has been suggested as a causative influence in the development and …
Chrysin treatment improves diabetes and its complications in liver, brain, and pancreas in streptozotocin-induced diabetic rats
S Samarghandian, M Azimi-Nezhad… - Canadian journal of …, 2016 - cdnsciencepub.com
Chrysin (CH) is a natural flavonoid with pharmacological influences. The purpose of the
current study was the assessment of possible protective effects of CH against oxidative …
current study was the assessment of possible protective effects of CH against oxidative …
New combination therapy of gliclazide and quercetin for protection against STZ-induced diabetic rats
NF Abdelkader, HE Eitah, YA Maklad, AA Gamaleldin… - Life sciences, 2020 - Elsevier
Aims The use of natural agents with anti-diabetic effect in combination therapy adds further
positive clinical implications in the management of diabetes mellitus. Interestingly, quercetin …
positive clinical implications in the management of diabetes mellitus. Interestingly, quercetin …
Chrysin induces antidiabetic, antidyslipidemic and anti-inflammatory effects in athymic nude diabetic mice
JJ Ramírez-Espinosa, J Saldaña-Ríos… - Molecules, 2017 - mdpi.com
Extensive knowledge of diabetes and its complications is helpful to find new drugs for proper
treatment to stop degenerative changes derived from this disease. In this context, chrysin (5 …
treatment to stop degenerative changes derived from this disease. In this context, chrysin (5 …
[HTML][HTML] Role of chrysin on expression of insulin signaling molecules
K Satyanarayana, K Sravanthi, IA Shaker… - Journal of Ayurveda …, 2015 - ncbi.nlm.nih.gov
Background: Currently available drugs are unsuccessful for the treatment of tye-2 diabetes
due to their adverseside-effects. Hence, a search for novel drugs, especially ofplant origin …
due to their adverseside-effects. Hence, a search for novel drugs, especially ofplant origin …
The effect of hesperidin and quercetin on oxidative stress, NF-κB and SIRT1 levels in a STZ-induced experimental diabetes model
Objective The aim of this study is to investigate the roles of SIRT1 and NF-κB in the
pathogenesis of diabetes mellitus in rats with STZ-induced diabetes and determine the …
pathogenesis of diabetes mellitus in rats with STZ-induced diabetes and determine the …
Impact of chrysin on the molecular mechanisms underlying diabetic complications
T Farkhondeh, S Samarghandian… - Journal of cellular …, 2019 - Wiley Online Library
Diabetes mellitus is a chronic metabolic disorder, resulting in high morbidity and mortality
worldwide. Neuropathy, ocular diseases, kidney diseases, and cardiovascular disease are …
worldwide. Neuropathy, ocular diseases, kidney diseases, and cardiovascular disease are …
[HTML][HTML] Chrysophyllum albidum fruit ethanol extract ameliorates hyperglycaemia and elevated blood pressure in streptozotocin-induced diabetic rats through …
AM Ajayi, ADA Adedapo, VB Badaki… - Biomedicine & …, 2021 - Elsevier
Oxidative stress and inflammation arising from hyperglycaemia have been identified as
important targets in mitigating hyperglycaemia-induced organ dysfunction in diabetics …
important targets in mitigating hyperglycaemia-induced organ dysfunction in diabetics …
Chrysin improves glucose and lipid metabolism disorders by regulating the AMPK/PI3K/AKT signaling pathway in insulin-resistant HepG2 cells and HFD/STZ-induced …
YJ Zhou, N Xu, XC Zhang, YY Zhu… - Journal of Agricultural …, 2021 - ACS Publications
Natural products with minor side effects have been reported to be an effective adjuvant
therapy for glucose and lipid metabolism disorders. Chrysin, a flavone, has a wide range of …
therapy for glucose and lipid metabolism disorders. Chrysin, a flavone, has a wide range of …
[HTML][HTML] Chrysoeriol ameliorates hyperglycemia by regulating the carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats
B Krishnan, AR Ganesan, R Balasubramani… - Food science and …, 2020 - Elsevier
The present study aimed to evaluate the effects of chrysoeriol from Cardiospermum
halicacabum in streptozotocin induced Wistar rats. Thirty rats were categorized as control …
halicacabum in streptozotocin induced Wistar rats. Thirty rats were categorized as control …