There is strong evidence on the interaction of several genetic variations and environmental
conditions in the etiology of asthma. Association of a disintegrin and metalloproteinase 33 …

Disintegrin and metalloprotease 33 (ADAM33) have been associated with childhood and
adult asthma in many populations. ADAM33 mutations might predispose to altered lung …

Asthma, affecting a growing number of populations, is a clinical condition with complex
cellular and genetic factors. Single nucleotide polymorphisms (SNPs) in gene coding for …

A disintegrin and metalloprotease domain 33 (ADAM33) is the first asthma-susceptible gene
discovered by positional cloning. The objective of this study was to determine the …

Background The gene encoding a disintegrin and metalloproteinase domain 33 (ADAM33)
is known to be associated with asthma in different ethnic groups. In Iraq, among the Arab …

Objective: A disintegrin and metalloproteinase 33 (ADAM33) gene has been considered as
an asthma susceptibility gene due to its possible role in airway remodeling, abnormal cell …

Asthma is one of the most common chronic respiratory diseases, affecting~ 300 million
children and adults worldwide. Previous studies identified a disintegrin and metalloprotease …

Abstract Background and Aim: Asthma is a very common disease involving genetic and
environmental factors. A disintegrin and metalloproteinase 33 (ADAM33) has been one of …

A disintegrin and metalloproteinase-encoding gene (ADAM33), was recently identified as an
asthma susceptibility gene. ADAM33 protein is expressed in smooth muscle cells of bronchi …

Objective Polymorphisms in ADAM33 gene have been implicated in susceptibility to the risk
of childhood asthma. However, the results remain controversial. We performed meta …