BAFF (B-cell–activating factor) is a critical survival factor for transitional and mature B cells
and is a promising therapeutic target for systemic lupus erythematosus (SLE). In 2010–2011 …

The B cell-stimulating molecules, BAFF (B cell activating factor) and APRIL (a proliferation-
inducing ligand), are critical factors in the maintenance of the B cell pool and humoral …

Introduction: The B-cell activating factor (BAFF) axis comprises two ligands (BAFF and
APRIL) and three receptors (BCMA, TACI, BR3). BAFF is a vital B-cell survival factor and …

B cell activating factor (BAFF) is a crucial survival factor for transitional and mature B cells,
and is a promising therapeutic target for systemic lupus erythematosus (SLE). A BAFF …

B-cell activating factor (BAFF), a member of the family of TNF-like cytokines, supports the
survival and differentiation of B cells. The successful development of belimumab, a human …

The B lymphocyte stimulator (BLyS)-A PRoliferation-Inducing Ligand (APRIL) signaling
pathway has an important role in the selection, maturation and survival of B cells and plays a …

BAFF (BLyS) and APRIL are TNF-like cytokines that support survival and differentiation of B
cells. Recent studies have discovered a role for BAFF in augmenting both innate and …

The B cell activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a B cell survival
factor which supports autoreactive B cells and prevents their deletion. BAFF expression is …

The BAFF system plays a key role in the development of autoimmunity, especially in
systemic lupus erythematosus (SLE). This often leads to the assumption that BAFF is mostly …

Abstract In November 2009, Human Genome Sciences and Glaxo‐Smith Kline [HGS
(Rockville, Maryland) and GSK, respectively] announced that Belimumab, a neutralizing …