[HTML][HTML] Modifiable risk factors for dementia, cognition, and plasma phosphorylated tau 181 in a large-scale cohort of Australian older adults
Abstract Alzheimer's disease (AD), the most common form of dementia, is preceded by years
of silent pathological change. Our objective was to examine the associations between …
of silent pathological change. Our objective was to examine the associations between …
Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real‐world population‐based cohort
PCL Ferreira, Y Zhang, B Snitz… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Plasma biomarkers—cost effective, non‐invasive indicators of Alzheimer's
disease (AD) and related disorders (ADRD)—have largely been studied in clinical research …
disease (AD) and related disorders (ADRD)—have largely been studied in clinical research …
Two-year prognostic utility of plasma p217+ tau across the Alzheimer's continuum
Background Plasma p217+ tau has shown high concordance with cerebrospinal fluid (CSF)
and positron emission tomography (PET) measures of amyloid-β (Aβ) and tau in Alzheimer's …
and positron emission tomography (PET) measures of amyloid-β (Aβ) and tau in Alzheimer's …
Predictive blood biomarkers and brain changes associated with age-related cognitive decline
TS Saunders, FE Pozzolo, A Heslegrave… - Brain …, 2023 - academic.oup.com
Growing evidence supports the use of plasma levels of tau phosphorylated at threonine 181,
amyloid-β, neurofilament light and glial fibrillary acidic protein as promising biomarkers for …
amyloid-β, neurofilament light and glial fibrillary acidic protein as promising biomarkers for …
Plasma p-tau181 level predicts neurodegeneration and progression to Alzheimer's dementia: a longitudinal study
YL Wang, J Chen, ZL Du, H Weng, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: Plasma-based biomarkers would be potential biomarkers for early diagnosis of
Alzheimer's disease (AD) because they are more available and cost-effective than …
Alzheimer's disease (AD) because they are more available and cost-effective than …
A novel ultrasensitive assay for plasma p‐tau217: performance in individuals with subjective cognitive decline and early Alzheimer's disease
F Gonzalez‐Ortiz, PCL Ferreira… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Detection of Alzheimer's disease (AD) pathophysiology among individuals
with mild cognitive changes and those experiencing subjective cognitive decline (SCD) …
with mild cognitive changes and those experiencing subjective cognitive decline (SCD) …
Association of plasma P-tau181 with memory decline in non-demented adults
Alzheimer's disease is the leading cause of dementia worldwide and is characterized by a
long preclinical phase in which amyloid-β and tau accumulate in the absence of cognitive …
long preclinical phase in which amyloid-β and tau accumulate in the absence of cognitive …
Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community study
Abstract Introduction Blood‐based Alzheimer's disease (AD) biomarkers provide
opportunities for community studies and across ethnic groups. We investigated blood …
opportunities for community studies and across ethnic groups. We investigated blood …
Objective subtle cognitive decline and plasma phosphorylated tau181: Early markers of Alzheimer's disease‐related declines
KR Thomas, KJ Bangen, EC Edmonds… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Objectively‐defined subtle cognitive decline (Obj‐SCD) and plasma
phosphorylated‐tau181 (p‐tau181) are promising early Alzheimer's disease (AD) markers …
phosphorylated‐tau181 (p‐tau181) are promising early Alzheimer's disease (AD) markers …
Plasma p‐tau217, p‐tau181, and NfL as early indicators of dementia risk in a community cohort: The Shanghai Aging Study
Z Xiao, W Wu, X Ma, J Wu, X Liang… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Blood biomarkers showed values for predicting future cognitive
impairment. Evidence from the community‐based cohort was limited only in high‐income …
impairment. Evidence from the community‐based cohort was limited only in high‐income …