[HTML][HTML] Modifiable risk factors for dementia, cognition, and plasma phosphorylated tau 181 in a large-scale cohort of Australian older adults

E Roccati, JM Collins, AD Bindoff, JE Alty, L Bartlett… - Neurobiology of …, 2023 - Elsevier
Abstract Alzheimer's disease (AD), the most common form of dementia, is preceded by years
of silent pathological change. Our objective was to examine the associations between …

Plasma biomarkers identify older adults at risk of Alzheimer's disease and related dementias in a real‐world population‐based cohort

PCL Ferreira, Y Zhang, B Snitz… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Plasma biomarkers—cost effective, non‐invasive indicators of Alzheimer's
disease (AD) and related disorders (ADRD)—have largely been studied in clinical research …

Two-year prognostic utility of plasma p217+ tau across the Alzheimer's continuum

A Feizpour, V Doré, JD Doecke, ZS Saad… - The Journal of …, 2023 - Springer
Background Plasma p217+ tau has shown high concordance with cerebrospinal fluid (CSF)
and positron emission tomography (PET) measures of amyloid-β (Aβ) and tau in Alzheimer's …

Predictive blood biomarkers and brain changes associated with age-related cognitive decline

TS Saunders, FE Pozzolo, A Heslegrave… - Brain …, 2023 - academic.oup.com
Growing evidence supports the use of plasma levels of tau phosphorylated at threonine 181,
amyloid-β, neurofilament light and glial fibrillary acidic protein as promising biomarkers for …

Plasma p-tau181 level predicts neurodegeneration and progression to Alzheimer's dementia: a longitudinal study

YL Wang, J Chen, ZL Du, H Weng, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
Background: Plasma-based biomarkers would be potential biomarkers for early diagnosis of
Alzheimer's disease (AD) because they are more available and cost-effective than …

A novel ultrasensitive assay for plasma p‐tau217: performance in individuals with subjective cognitive decline and early Alzheimer's disease

F Gonzalez‐Ortiz, PCL Ferreira… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Detection of Alzheimer's disease (AD) pathophysiology among individuals
with mild cognitive changes and those experiencing subjective cognitive decline (SCD) …

Association of plasma P-tau181 with memory decline in non-demented adults

J Therriault, AL Benedet, TA Pascoal… - Brain …, 2021 - academic.oup.com
Alzheimer's disease is the leading cause of dementia worldwide and is characterized by a
long preclinical phase in which amyloid-β and tau accumulate in the absence of cognitive …

Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community study

AM Brickman, JJ Manly, LS Honig… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Introduction Blood‐based Alzheimer's disease (AD) biomarkers provide
opportunities for community studies and across ethnic groups. We investigated blood …

Objective subtle cognitive decline and plasma phosphorylated tau181: Early markers of Alzheimer's disease‐related declines

KR Thomas, KJ Bangen, EC Edmonds… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Objectively‐defined subtle cognitive decline (Obj‐SCD) and plasma
phosphorylated‐tau181 (p‐tau181) are promising early Alzheimer's disease (AD) markers …

Plasma p‐tau217, p‐tau181, and NfL as early indicators of dementia risk in a community cohort: The Shanghai Aging Study

Z Xiao, W Wu, X Ma, J Wu, X Liang… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Blood biomarkers showed values for predicting future cognitive
impairment. Evidence from the community‐based cohort was limited only in high‐income …