Chronic demyelination and axonal degeneration in multiple sclerosis: pathogenesis and therapeutic implications
TJ Simkins, GJ Duncan, D Bourdette - Current neurology and …, 2021 - Springer
Abstract Purpose of Review Multiple sclerosis (MS) is the most common demyelinating
disease of the central nervous system (CNS). Inflammatory attacks in MS lead to both …
disease of the central nervous system (CNS). Inflammatory attacks in MS lead to both …
Inflammation, demyelination, neurodegeneration and neuroprotection in the pathogenesis of multiple sclerosis
LK Peterson, RS Fujinami - Journal of neuroimmunology, 2007 - Elsevier
Although axonal loss has been observed in demyelinated multiple sclerosis (MS) lesions,
there has been a major focus on understanding mechanisms of demyelination. However …
there has been a major focus on understanding mechanisms of demyelination. However …
Neurodegeneration in multiple sclerosis
GM Mey, KR Mahajan… - WIREs mechanisms of …, 2023 - Wiley Online Library
Axonal loss in multiple sclerosis (MS) is a key component of disease progression and
permanent neurologic disability. MS is a heterogeneous demyelinating and …
permanent neurologic disability. MS is a heterogeneous demyelinating and …
Neuroprotection and repair in multiple sclerosis
Multiple sclerosis (MS) is an inflammatory demyelinating disease that is considered by many
people to have an autoimmune aetiology. In recent years, new data emerging from …
people to have an autoimmune aetiology. In recent years, new data emerging from …
Role of oligodendrocyte dysfunction in demyelination, remyelination and neurodegeneration in multiple sclerosis
AO Dulamea - Multiple Sclerosis: Bench to Bedside: Global …, 2017 - Springer
Oligodendrocytes (OLs) are the myelinating cells of the central nervous system (CNS) during
development and throughout adulthood. They result from a complex and well controlled …
development and throughout adulthood. They result from a complex and well controlled …
The pathology of multiple sclerosis
CF Lucchinetti, J Parisi, W Bruck - Neurologic clinics, 2005 - neurologic.theclinics.com
Multiple sclerosis (MS) is a chronic neurologic disease affecting approximately 1 million
adults worldwide and 300,000 Americans [1]. Early illustrations by Carswell in 1838 and …
adults worldwide and 300,000 Americans [1]. Early illustrations by Carswell in 1838 and …
Mechanisms of neuronal dysfunction and degeneration in multiple sclerosis
R Dutta, BD Trapp - Progress in neurobiology, 2011 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system. Due to its high prevalence, MS is the leading cause of non-traumatic …
nervous system. Due to its high prevalence, MS is the leading cause of non-traumatic …
Axonal loss in multiple sclerosis: causes and mechanisms
G Criste, B Trapp, R Dutta - Handbook of clinical neurology, 2014 - Elsevier
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system and the leading cause of non-traumatic neurologic disability in young adults …
nervous system and the leading cause of non-traumatic neurologic disability in young adults …
Inflammation and degeneration in multiple sclerosis
W Brück, C Stadelmann - Neurological Sciences, 2003 - Springer
Multiple (MS) sclerosis is a chronic inflammatory demyelinating disease of the central
nervous system with the pathological hallmarks of inflammation, demyelination, axon loss …
nervous system with the pathological hallmarks of inflammation, demyelination, axon loss …
[HTML][HTML] Diverse targets for intervention during inflammatory and neurodegenerative phases of multiple sclerosis
SS Zamvil, L Steinman - Neuron, 2003 - cell.com
Multiple sclerosis (MS) is an autoimmune central nervous system (CNS) demyelinating
disease that causes relapsing and chronic neurologic impairment. Recent observations …
disease that causes relapsing and chronic neurologic impairment. Recent observations …