Angiogenic factors and their role in pathogenesis and prediction of preeclampsia

H Stepan, A Jank - Zeitschrift fur Geburtshilfe und Neonatologie, 2009 - europepmc.org
Angiogenic factors like placental growth factor (PlGF) and its anti-angiogenic antagonists
soluble fms-like tyrosine kinase 1 (sFlt1) and soluble endoglin (sEng) are closely related to …

Predictive value of maternal angiogenic factors in second trimester pregnancies with abnormal uterine perfusion

H Stepan, A Unversucht, N Wessel, R Faber - Hypertension, 2007 - Am Heart Assoc
Angiogenic factors like placental growth factor and its antiangiogenic antagonist soluble fms-
like tyrosine kinase 1 (sFlt1) are closely related to the pathogenesis of preeclampsia and …

Angiogenic factors for prediction of preeclampsia and intrauterine growth restriction onset in high-risk women: AngioPred study

T Raia-Barjat, C Prieux, JC Gris… - The Journal of …, 2019 - Taylor & Francis
Objective: The study aimed to compare the level of two angiogenic factors, soluble fms-like
tyrosine kinase-1 (sFlt1) and soluble endoglin (sEng), for the prediction of preeclampsia and …

Maternal, gestational and neonatal characteristics and maternal angiogenic factors in normotensive pregnancies

AC Staff, NK Harsem, K Braekke, M Hyer… - European Journal of …, 2009 - Elsevier
OBJECTIVE: Alterations in maternal circulating angiogenic factors are proposed to result in
hypertension and proteinuria and development of preeclampsia. The aim of this study was to …

Angiogenic factors sFlt-1 and PlGF in preeclampsia: Prediction of risk and prognosis in a high-risk obstetric population

C Tardif, E Dumontet, H Caillon, E Misbert… - Journal of gynecology …, 2018 - Elsevier
Objectives Despite its simple definition, preeclampsia can have variable and atypical clinical
presentations, an unpredictable course, and potential adverse maternal and fetal outcomes …

One-third of patients with eclampsia at term do not have an abnormal angiogenic profile

T Chaiworapongsa, R Romero, F Gotsch… - Journal of Perinatal …, 2023 - degruyter.com
Objectives An abnormal angiogenic profile is present in about one-half of women with
preeclampsia at term. Few studies examined the roles of angiogenic biomarkers in …

Sequential changes in antiangiogenic factors in early pregnancy and risk of developing preeclampsia

S Rana, SA Karumanchi, RJ Levine, S Venkatesha… - …, 2007 - Am Heart Assoc
Concentrations of soluble fms-like tyrosine kinase 1 (sFlt1) and soluble endoglin (sEng)
increase in maternal blood with the approach of clinical preeclampsia. Although alterations …

Angiogenic markers predict pregnancy complications and prolongation in preeclampsia: continuous versus cutoff values

L Saleh, Y Vergouwe, AH van den Meiracker… - …, 2017 - Am Heart Assoc
To assess the incremental value of a single determination of the serum levels of sFlt-1
(soluble Fms-like tyrosine kinase 1) and PlGF (placental growth factor) or their ratio, without …

[HTML][HTML] Clinical interpretation and implementation of the sFlt-1/PlGF ratio in the prediction, diagnosis and management of preeclampsia

S Verlohren, SP Brennecke, A Galindo… - Pregnancy …, 2022 - Elsevier
Preeclampsia is associated with significant morbidity and mortality for mother and baby.
Although around 30% of all pregnancies are evaluated for preeclampsia, diagnosis is …

Similar Pro-and antiangiogenic profiles close to delivery in different clinical presentations of two pregnancy syndromes: preeclampsia and fetal growth restriction

W Dymara-Konopka, M Laskowska… - International Journal of …, 2023 - mdpi.com
The purpose of this study was to evaluate serum levels of anti-and pro-angiogenic
substances measured using enzyme-linked immunosorbent assays and their ratios in …