Introduction Although randomised controlled trials have demonstrated that preoperative
glucocorticoids may improve postoperative surrogate outcomes among patients undergoing …

Background Cardiac surgery triggers a strong inflammatory reaction, which carries
significant clinical consequences. Corticosteroids have been suggested as a potential …

Corticosteroids are commonly used in the peri-operative setting for patients undergoing
cardiac surgery with cardiopulmonary bypass (CPB). The inflammatory response to CPB is …

Patients previously on corticosteroids within 1 year before surgery are routinely treated with
perioperative high-dose corticosteroids. However, there is little evidence to support this …

BACKGROUND: Steroid-treated patients undergoing major colorectal surgery are routinely
treated with high-dose steroids (HDS) to prevent perioperative adrenal insufficiency and …

Background Preoperative steroid use has been associated with worse surgical outcomes.
The purpose of this study was to determine whether laparoscopic surgery reduces the risk of …

Context Prophylactic corticosteroids are often administered during cardiac surgery to
attenuate the inflammatory response to cardiopulmonary bypass and surgical trauma; …

Importance High-dose glucocorticoids (GCs) are routinely given to surgical patients with a
history of GC exposure to prevent perioperative acute adrenal insufficiency, but this practice …

BACKGROUND: High-dose perioperative corticosteroids are the standard of care for steroid-
treated patients undergoing surgery. There is little evidence, however, to support this …

OBJECTIVE: Cardiac surgery and cardiopulmonary bypass (CPB) induce an acute
inflammatory response contributing to postoperative morbidity. The use of steroids as anti …