Objective: The most common malignancy in women is breast cancer worldwide. Previous
studies performed in different populations have suggested an association between Multi …

Objective: Breast cancer is known as the most prevalent cancer among women and the
second most common cancer in the world. Different studies mentioned the …

: Background: Resistance to drugs with different structure and function is a great obstacle to
the successful treatment of breast cancer. A well-known mechanism responsible for drug …

The human multidrug resistance gene 1 (MDR1) encodes a plasma membrane, P-
glycoprotein (Pgp), which functions as the transmembrane efflux pump for various …

Background: Breast cancer is the leading cause of cancer death among women and the
second in humans worldwide. Many published studies have suggested an association …

Abstract The C3435T (rs1045642) polymorphism, located in multi-drug resistance gene 1
(MDR1), has demonstrated its role in decreasing the P-gp activity level which is related to …

Breast cancer (BC) is the most common cancer among women in the world. The human
multidrug resistance 1 gene (MDR1) is potentially an important gene influencing the …

The human multidrug resistance 1 gene (MDR1) is an important candidate gene influencing
the susceptibility to various diseases, including breast cancer. The object of this study was to …

Abstract Multidrug resistance 1 (MDR1) is a transmembrane transporter on the cell
membrane. As an ATP‑dependent efflux pump, MDR1 is mainly responsible for the …

The multidrug resistance 1 gene (MDR1) is an important candidate gene for influencing
breast cancer susceptibility. This study aimed to evaluate the association between MDR1 …