[HTML][HTML] Role of endocrine PACAP in age-related diseases

D Toth, D Reglodi, L Schwieters… - Frontiers in Endocrinology, 2023 - frontiersin.org
Pituitary adenylate cyclase activating polypeptide (PACAP) is a conserved neuropeptide,
which confers diverse anti-aging endocrine and paracrine/autocrine effects, including anti …

PACAP as a potential biomarker: alterations of PACAP levels in human physiological and pathological conditions

D Reglodi, Z Helyes, J Nemeth, RA Vass… - Pituitary adenylate …, 2016 - Springer
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with wide
distribution and diverse effects. Its presence has not only been revealed in the nervous …

PACAP deficiency as a model of aging

D Reglodi, T Atlasz, E Szabo, A Jungling, A Tamas… - Geroscience, 2018 - Springer
Dysregulation of neuropeptides may play an important role in aging-induced impairments. In
the long list of neuropeptides, pituitary adenylate cyclase–activating polypeptide (PACAP) …

[HTML][HTML] Protective effects of PACAP in peripheral organs

D Toth, E Szabo, A Tamas, T Juhasz… - Frontiers in …, 2020 - frontiersin.org
Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide widely
distributed in the nervous system, where it exerts strong neuroprotective effects. PACAP is …

Examination of pituitary adenylate cyclase-activating polypeptide (PACAP) as a potential biomarker in heart failure patients

Z Sarszegi, D Szabo, B Gaszner, A Konyi… - Journal of Molecular …, 2019 - Springer
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic and
multifunctional neuropeptide having neurotrophic, neuroprotective, and general …

[HTML][HTML] The neuropeptide pituitary adenylate cyclase-activating polypeptide (PACAP) is protective in inflammation and oxidative stress-induced damage in the kidney

G Horvath, B Opper, D Reglodi - International Journal of Molecular …, 2019 - mdpi.com
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide
with a widespread distribution throughout the entire body including the urinary system …

Strategies to convert PACAP from a hypophysiotropic neurohormone into a neuroprotective drug

S Bourgault, D Chatenet, O Wurtz… - Current …, 2011 - ingentaconnect.com
In neurological insults, such as cerebral ischemia and traumatic brain injury, complex
molecular mechanisms involving inflammation and apoptosis are known to cause severe …

[HTML][HTML] Neuroprotective roles of pituitary adenylate cyclase-activating polypeptide in neurodegenerative diseases

EH Lee, SR Seo - BMB reports, 2014 - ncbi.nlm.nih.gov
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic bioactive peptide
that was first isolated from an ovine hypothalamus in 1989. PACAP belongs to the …

PACAP immunoreactivity in human malignant tumor samples and cardiac diseases

Z Szanto, Z Sarszegi, D Reglodi, J Nemeth… - Journal of Molecular …, 2012 - Springer
Pituitary adenylate cyclase activating polypeptide (PACAP) is a pleiotropic and
multifunctional neuropeptide having important roles in various physiological processes …

Proteomics of rat hypothalamus, hippocampus and pre-frontal/frontal cortex after central administration of the neuropeptide PACAP

L Gasperini, C Piubelli, L Carboni - Molecular biology reports, 2012 - Springer
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that exerts
pleiotropic functions, acting as a hypophysiotropic factor, a neurotrophic and a …