Age-related deviations of the immune system contribute to a higher likelihood of infections,
cancer, and autoimmunity in the elderly. Senescence of T-lymphocytes is characterized by …

Aging leads to a decline in immune cell function, which leaves the organism vulnerable to
infections and age-related multimorbidities. One major player of the adaptive immune …

Increasing age has been associated with an insufficient protection following vaccination and
an increased incidence and severity of infectious diseases. The predicted acceleration of …

The innate and adaptive branches of the immune system display changes with aging, a fact
referred to as immunosenescence. Furthermore, it has been established that adaptive …

Although advances in preventive medicine have greatly improved prognosis, cardiovascular
disease (CVD) remains the leading cause of death worldwide. This clearly indicates that …

Advancing age is accompanied by changes in immune potential, frequently characterized as
declines in the capacity to mount effective cell-mediated or humoral immune responses …

The immune system exhibits profound age-related changes, collectively termed
immunosenescence. The most visible of these is the decline in protective immunity, which …

Age-related immunosenescence is characterized by progressive dysfunction of adaptive
immune response and increased autoimmunity. Nevertheless, the impact of aging on CD4+ …

Aging represents an emerging challenge for public health due to the declined immune
responses against pathogens, weakened vaccination efficacy, and disturbed tissue …

Changes in the T-lymphocyte compartment represent the most critical component of
immunological aging. Recent studies have demonstrated that the age-related decline in T …