Pharmacological treatment of stable chronic obstructive pulmonary disease

D Singh - Respirology, 2021 - Wiley Online Library
Pharmacological treatment for chronic obstructive pulmonary disease (COPD) aims to
alleviate symptoms and reduce the future risk of events such as exacerbations, disease …

[HTML][HTML] COPD treatment–a conceptual review based on critical endpoints

A Roque, L Taborda-Barata, ÁA Cruz, G Viegi… - Pulmonology, 2023 - Elsevier
Introduction Chronic obstructive pulmonary disease (COPD) is one of the main causes of
death and disability worldwide. Many treatment options are now available, but criteria for …

Triple therapy in COPD: what we know and what we don't

PMA Calverley, H Magnussen… - COPD: Journal of …, 2017 - Taylor & Francis
Triple inhaled therapy for chronic obstructive pulmonary disease (COPD) consists of an
inhaled corticosteroid (ICS), a long-acting β2-agonist (LABA) and a long-acting muscarinic …

Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019

D Singh, A Agusti, A Anzueto, PJ Barnes… - European …, 2019 - Eur Respiratory Soc
Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …

Blood eosinophils and treatment response with triple and dual combination therapy in chronic obstructive pulmonary disease: analysis of the IMPACT trial

S Pascoe, N Barnes, G Brusselle… - The Lancet …, 2019 - thelancet.com
Background Previous studies have highlighted a relationship between reduction in rate of
exacerbations with therapies containing inhaled corticosteroids (ICS) and baseline blood …

New perspectives on chronic obstructive pulmonary disease

BR Celli, D Singh, C Vogelmeier… - International Journal of …, 2022 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide; many recent advances have been made in many aspects of the disease. The aim …

[HTML][HTML] In 'real world'patients with COPD, exacerbation history, and not blood eosinophils, is the most reliable predictor of future exacerbations

H Worth, R Buhl, CP Criée, P Kardos, E Gückel… - Respiratory …, 2023 - Springer
Introduction There is an interest in the role of blood eosinophils for predicting inhaled
corticosteroid (ICS) response in chronic obstructive pulmonary disease (COPD). Most data …

Blood eosinophils as a marker of response to inhaled corticosteroids in COPD

NC Barnes, R Sharma, S Lettis… - European Respiratory …, 2016 - Eur Respiratory Soc
Identification of a biomarker that predicts response to inhaled corticosteroids (ICS) would
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …

[HTML][HTML] Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials

D Singh, JA Wedzicha, S Siddiqui, A de la Hoz… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …

[Translated article] Spanish COPD guidelines (GesEPOC) 2021: Updated pharmacological treatment of stable COPD

M Miravitlles, M Calle, J Molina, P Almagro… - Archivos de …, 2022 - Elsevier
Abstract The Spanish COPD Guidelines (GesEPOC) were first published in 2012, and since
then have undergone a series of updates incorporating new evidence on the diagnosis and …