In an era of precision medicine, it seems regressive that we do not use stratified approaches
to direct treatment of oral corticosteroids during an exacerbation of chronic obstructive …

Clinical trials in chronic obstructive pulmonary disease (COPD) patients have shown that the
long-term use of inhaled corticosteroids (ICS) in COPD patients reduced the number of …

Highlights•COPD affects millions worldwide.•Current treatment is directed at symptom
improvement.•There is improved understanding of mechanisms underlying COPD.•With …

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease that is
characterized by progressive airway obstruction that, unlike asthma, is relatively insensitive …

Introduction To date, there is solid evidence from randomized controlled trials (RCTs)
supporting the rationale for withdrawal from inhaled corticosteroids (ICSs) in most patients …

Background Blood eosinophil counts might predict response to inhaled corticosteroids (ICS)
in patients with chronic obstructive pulmonary disease (COPD) and a history of …

ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
complex disease with great morbidity and mortality. Despite the new developments in the …

There are an estimated 12 million patients with COPD in the United States, where this
disease is now the third leading cause of death, claiming close to 140,000 American lives …

ABSTRACT Introduction The Global Initiative for Chronic Obstructive Lung Disease (GOLD)
strategy report provides guidance on effective management of chronic obstructive …

Background Guidelines for the treatment of chronic obstructive pulmonary disease (COPD)
patients with multiple exacerbations and eosinophilia recommend a long-acting beta 2 …