miR-130b regulates gap junctional intercellular communication through connexin 43 in granulosa cells from patients with polycystic ovary syndrome

L Jiang, H Huang, Y Qian, Y Li, X Chen… - Molecular human …, 2020 - academic.oup.com
MicroRNAs (miRNAs) are small, noncoding RNAs that negatively regulate gene expression
post-transcriptionally. We explored whether connexin 43 (Cx43) was differently expressed in …

Dysregulated miR-142,-33b and-423 in granulosa cells target TGFBR1 and SMAD7: a possible role in polycystic ovary syndrome

Y Li, Y Xiang, Y Song, L Wan, G Yu… - Molecular Human …, 2019 - academic.oup.com
It is well established that microRNA (miRNA) expression profiles are altered in patients with
polycystic ovary syndrome (PCOS). In addition, abnormal transforming growth factor beta …

MicroRNA-141 and MicroRNA-200c are overexpressed in granulosa cells of polycystic ovary syndrome patients

T He, Y Liu, Y Jia, H Wang, X Yang, G Lu, H Liu… - Frontiers in …, 2018 - frontiersin.org
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
reproductive-aged women, affecting 6–8% of women and characterized by …

Expression of miR-15a, miR-145, and miR-182 in granulosa-lutein cells, follicular fluid, and serum of women with polycystic ovary syndrome (PCOS)

M Naji, S Nekoonam, A Aleyasin, E Arefian… - Archives of gynecology …, 2018 - Springer
Purpose Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies
that affects women in reproductive age. MicroRNAs (miRNAs) play crucial roles in normal …

MiRNAs regulating insulin sensitivity are dysregulated in polycystic ovary syndrome (PCOS) ovaries and are associated with markers of inflammation and insulin …

F Cirillo, C Catellani, P Lazzeroni, C Sartori… - Frontiers in …, 2019 - frontiersin.org
Objective: MicroRNAs (miRNAs) are gene expression regulators. Altered miRNA levels are
associated with diabetes, insulin resistance, and inflammation. Insulin resistance and …

MicroRNA-93 promotes ovarian granulosa cells proliferation through targeting CDKN1A in polycystic ovarian syndrome

L Jiang, J Huang, L Li, Y Chen, X Chen… - The Journal of …, 2015 - academic.oup.com
Context: MicroRNAs (miRNAs) are small, noncoding RNAs that negatively regulate gene
expression post-transcriptionally. Whether differently expressed miRNAs contribute to …

[HTML][HTML] The role of Connexin26 regulated by MiR-2114-3p in the pathogenesis of ovarian cancer

Y Li, L Wang, J Tian, Y Zu, F Wang, S Ma, J Cao… - Biochemical and …, 2023 - Elsevier
Objectives The purpose of our research was to determine the expression of Cx26 and miR-
2114-3p, and their effects on proliferation, migration, and invasion in ovarian cancer and …

miR‑206 serves an important role in polycystic ovary syndrome through modulating ovarian granulosa cell proliferation and apoptosis

J Zhou, X Jin, Z Sheng, Z Zhang - Experimental and …, 2021 - spandidos-publications.com
An increasing number of studies have reported that microRNAs (miRNAs) have an important
role in polycystic ovary syndrome (PCOS). Downregulation of miR‑206 in patients with …

MicroRNA-145 negatively regulates cell proliferation through targeting IRS1 in isolated ovarian granulosa cells from patients with polycystic ovary syndrome

G Cai, X Ma, B Chen, Y Huang, S Liu… - Reproductive …, 2017 - journals.sagepub.com
Polycystic ovary syndrome (PCOS) is a complex, heterogeneous endocrine and metabolic
disorder affecting 5% to 10% of reproductive-age women. A high rate of granulosa cell (GC) …

[HTML][HTML] MicroRNA-125b controls growth of ovarian granulosa cells in polycystic ovarian syndrome by modulating cyclin B1 expression

J Deng, C Li, J Luo, J Xie, C Peng… - Archives of Medical …, 2022 - ncbi.nlm.nih.gov
Results The miR-125b transcript levels were considerably high in polycystic ovaries and
ovarian granulosa KGN cells. The inhibition of miR-125b expression decreased the viability …