The role of gender pharmacogenetics in the personalization of drug treatment

E Cecchin, B Posocco, S Mezzalira… - … of Pharmacology and …, 2023 - ASPET
The use of pharmacogenetic guidelines in personalizing treatments has shown the potential
to reduce interindividual variability in drug response by enabling genotype-matched dosing …

The effects of sex on pharmacogenetically guided drug treatment

S Mezzalira, G Toffoli - Pharmacogenomics, 2021 - Future Medicine
The effects of sex on pharmacogenetically guided drug treatment | Pharmacogenomics Future
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En route to precision medicine through the integration of biological sex into pharmacogenomics

L Gaignebet, G Kararigas - Clinical Science, 2017 - portlandpress.com
Frequently, pharmacomechanisms are not fully elucidated. Therefore, drug use is linked to
an elevated interindividual diversity of effects, whether therapeutic or adverse, and the role …

Current progress in pharmacogenetics

JD Blakey, IP Hall - British journal of clinical pharmacology, 2011 - Wiley Online Library
The study of genetic variation has the potential to aid understanding of the mechanisms
underlying the observed inter‐individual variation in drug response and by which …

Pharmacogenomics: ensuring equity regarding drugs based on genetic difference

PG Epps, MA Rothstein - Pharmacogenomics: The Search for …, 2002 - Wiley Online Library
Certain genetic polymorphisms relevant to drug response occur with varying frequency
among different ethnic groups. With its focus on genetic variations among individuals …

Race, ethnicity, ancestry, and pharmacogenetics

TJ Urban - Mount Sinai Journal of Medicine: A Journal of …, 2010 - Wiley Online Library
Pharmacogenetics is the study of how genetic variation influences the response to drugs.
The concepts of race, ethnicity, and ancestry have long had a strong influence on …

The role of ethnicity in variability in response to drugs: focus on clinical pharmacology studies

SU Yasuda, L Zhang, SM Huang - Clinical Pharmacology & …, 2008 - Wiley Online Library
Ethnicity is one factor that may account for the observed differences in both
pharmacokinetics (PK) and pharmacodynamics (PD) of drugs, resulting in variability in …

Pharmacogenetics for the prescriber

M Pirmohamed - Medicine, 2012 - Elsevier
Pharmacogenetics is the study of how genetic factors affect the response to drugs (efficacy
and toxicity). Variation in genes can affect either a drug's pharmacokinetics (how the drug is …

The interface between pharmacoepidemiology and pharmacogenetics

AH Maitland-van der Zee, A de Boer… - European journal of …, 2000 - Elsevier
One of the most challenging areas of research in pharmacoepidemiology is to understand
why individuals respond differently to drug therapy, both in terms of beneficial and adverse …

Race and ethnicity in the era of emerging pharmacogenomics

L Harty, K Johnson, A Power - The Journal of Clinical …, 2006 - Wiley Online Library
Race and ethnicity are terms that are commonly used to categorize subjects in medical
research. Advances in genetics and the emerging discipline of pharmacogenomics have …