Rheumatoid arthritis patients treated in trial and real world settings: comparison of randomized trials with registries
G Kilcher, N Hummel, EM Didden, M Egger… - …, 2018 - academic.oup.com
Objective To investigate whether patients with RA enrolled in randomized controlled trials
(RCTs) and observational studies may differ in terms of characteristics that could modify …
(RCTs) and observational studies may differ in terms of characteristics that could modify …
QUEST-RA: quantitative clinical assessment of patients with rheumatoid arthritis seen in standard rheumatology care in 15 countries
T Sokka, H Kautiainen, S Toloza, H Mäkinen… - Annals of the …, 2007 - ard.bmj.com
Objective: To conduct a cross-sectional review of non-selected consecutive outpatients with
rheumatoid arthritis (RA) as part of standard clinical care in 15 countries for an overview of …
rheumatoid arthritis (RA) as part of standard clinical care in 15 countries for an overview of …
Comparative effectiveness of biologics for the management of rheumatoid arthritis: systematic review and network meta-analysis
R Alfonso-Cristancho, N Armstrong, R Arjunji… - Clinical …, 2017 - Springer
Our aim was to establish the comparative effectiveness of rheumatoid arthritis (RA)
biologics, using a systematic review and network meta-analysis. The systematic review used …
biologics, using a systematic review and network meta-analysis. The systematic review used …
Comparative effectiveness of abatacept, rituximab, tocilizumab and TNFi biologics in RA: results from the nationwide Swedish register
T Frisell, M Dehlin, D Di Giuseppe, N Feltelius… - …, 2019 - academic.oup.com
Objectives Current guidelines rank abatacept, rituximab, tocilizumab and TNF-inhibitors
(TNFi) as having equal effectiveness for the treatment of RA, at least as second line …
(TNFi) as having equal effectiveness for the treatment of RA, at least as second line …
Low‐versus high‐dose rituximab for rheumatoid arthritis: a systematic review and meta‐analysis
M Bredemeier, FK de Oliveira… - Arthritis care & …, 2014 - Wiley Online Library
Objective The approved dose of rituximab (RTX) for rheumatoid arthritis (RA) is 2× 1,000 mg
infusions given 2 weeks apart. There is contradictory evidence regarding the effectiveness of …
infusions given 2 weeks apart. There is contradictory evidence regarding the effectiveness of …
Tumour necrosis factor inhibition versus rituximab for patients with rheumatoid arthritis who require biological treatment (ORBIT): an open-label, randomised controlled …
D Porter, J Van Melckebeke, J Dale, CM Messow… - The Lancet, 2016 - thelancet.com
Background Tumour necrosis factor (TNF) inhibition and B-cell depletion are highly effective
treatments for active rheumatoid arthritis, but so far no randomised controlled trials have …
treatments for active rheumatoid arthritis, but so far no randomised controlled trials have …
A comparison of patient characteristics and outcomes in selected European and US rheumatoid arthritis registries
JR Curtis, A Jain, J Askling, SL Bridges Jr… - Seminars in arthritis and …, 2010 - Elsevier
PURPOSE: Randomized controlled trials (RCTs) have demonstrated the efficacy of biologic
agents in the treatment of rheumatic diseases. However, results from RCTs may not be …
agents in the treatment of rheumatic diseases. However, results from RCTs may not be …
Treating rheumatoid arthritis to target: recommendations of an international task force
JS Smolen, D Aletaha, JWJ Bijlsma… - Annals of the …, 2010 - ard.bmj.com
Background Aiming at therapeutic targets has reduced the risk of organ failure in many
diseases such as diabetes or hypertension. Such targets have not been defined for …
diseases such as diabetes or hypertension. Such targets have not been defined for …
Use of a “critical difference” statistical criterion improves the predictive utility of the Health Assessment Questionnaire-Disability Index score in patients with rheumatoid …
F Behrens, M Koehm, EC Schwaneck, M Schmalzing… - BMC rheumatology, 2019 - Springer
Abstract Background The Health Assessment Questionnaire-Disability Index (HAQ-DI) is
used to assess functional status in rheumatoid arthritis (RA), but the change required for …
used to assess functional status in rheumatoid arthritis (RA), but the change required for …
Can rheumatoid arthritis (RA) registries provide contextual safety data for modern RA clinical trials? The case for mortality and cardiovascular disease
Background We implemented a novel method for providing contextual adverse event rates
for a randomised controlled trial (RCT) programme through coordinated analyses of five RA …
for a randomised controlled trial (RCT) programme through coordinated analyses of five RA …
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