MicroRNA target prediction and validation

G Thillaiyampalam, AS Cristino - MicroRNA, 2022 - Elsevier
MicroRNAs (miRNAs) are an evolutionarily conserved component of gene regulatory
networks and essential for the development and maintenance of all multicellular organisms …

[HTML][HTML] Determinants of Functional MicroRNA Targeting

H Hwang, HR Chang, D Baek - Molecules and cells, 2023 - Elsevier
MicroRNAs (miRNAs) play cardinal roles in regulating biological pathways and processes,
resulting in significant physiological effects. To understand the complex regulatory network …

Recent development of bioinformatics tools for microRNA target prediction

MS Khatun, MA Alam, W Shoombuatong… - Current Medicinal …, 2022 - ingentaconnect.com
MicroRNAs (miRNAs) are central players that regulate the post-transcriptional processes of
gene expression. Binding of miRNAs to target mRNAs can repress their translation by …

Challenges in microRNAs' targetome prediction and validation

JER Arias, V Busskamp - Neural regeneration research, 2019 - journals.lww.com
MicroRNAs (miRNAs) are small RNA molecules with important roles in post-transcriptional
regulation of gene expression. In recent years, the predicted number of miRNAs has …

Computational biology in microRNA

Y Li, Z Zhang - Wiley Interdisciplinary Reviews: RNA, 2015 - Wiley Online Library
MicroRNA (miRNA) is a class of small endogenous noncoding RNA species, which regulate
gene expression post‐transcriptionally by forming imperfect base‐pair at the 3 …

A practical guide to miRNA target prediction

MM Akhtar, L Micolucci, MS Islam, F Olivieri… - … : Methods and Protocols, 2019 - Springer
MicroRNAs (miRNAs) are small endogenous noncoding RNA molecules that
posttranscriptionally regulate gene expression. Since their discovery, a huge number of …

Computational tools for microRNA target prediction

NS Ab Mutalib, SA Sulaiman, R Jamal - Computational epigenetics and …, 2019 - Elsevier
MicroRNAs (miRNAs) are short, noncoding RNA species which play important roles in gene
regulation. With the advancement in the next-generation sequencing technologies, many …

DIANA-microT web server: elucidating microRNA functions through target prediction

M Maragkakis, M Reczko, VA Simossis… - Nucleic acids …, 2009 - academic.oup.com
Computational microRNA (miRNA) target prediction is one of the key means for deciphering
the role of miRNAs in development and disease. Here, we present the DIANA-microT web …

One decade of development and evolution of microRNA target prediction algorithms

PH Reyes∼ Herrera, E Ficarra - Genomics, Proteomics and …, 2012 - academic.oup.com
Nearly two decades have passed since the publication of the first study reporting the
discovery of microRNAs (miRNAs). The key role of miRNAs in post-transcriptional gene …

miRDB: an online database for prediction of functional microRNA targets

Y Chen, X Wang - Nucleic acids research, 2020 - academic.oup.com
MicroRNAs (miRNAs) are small noncoding RNAs that act as master regulators in many
biological processes. miRNAs function mainly by downregulating the expression of their …