Staphylococcus enterotoxins bind class II MHC molecules on antigen-presenting cells (APC)
and stimulate T cells expressing appropriate Vβ gene products. Although the role of non …

Superantigens (SAgs) are extremely potent bacterial toxins, which evoke a virulent immune
response, inducing nonspecific T-cell proliferation, rapid cytokine release, and lethal toxic …

Abstract B7-1 and B7-2 are costimulatory molecules expressed on antigen-presenting cells.
The CD28/B7 costimulation pathway is critical for T-cell activation, proliferation, and Th …

Anti-CD25 Immunotherapy: Regulating the Regulators | Science Translational Medicine news
careers commentary Journals Science Science brought to you byGoogle Indexer Log in science …

Several antibody-targeting cancer immunotherapies have been developed based on T cell
activation at the target cells. One of the most potent activators of T cells are bacterial …

Superantigens are interesting for several reasons. They exhibit unusual T-cell activation
characteristics, they allow to follow in vivo ligand-reactive T cells, they cause T-cell-mediated …

We examined the efficacy of using monoclonal antibodies to target antigen (avidin) to
different surface molecules expressed on antigen presenting cells (APC). In particular, we …

It just dawned on me that two and a half years ago I began the wonderful journey with you to
get my health back, and I did not just lose one hundred pounds; I haven't had a virus, cold, or …

Superantigens (SAgs) are microbial toxins defined by their ability to activate T lymphocytes
in a T cell receptor (TCR) β-chain variable domain (Vβ)-specific manner. Although existing …

Immune responses must be tightly regulated to ensure both optimal protective immunity and
tolerance. Costimulatory pathways within the B7: CD28 family provide essential signals for …