The opportunistic fungal pathogen Aspergillus fumigatus adapts to iron limitation by
upregulation of iron uptake mechanisms including siderophore biosynthesis and …

Microorganisms have to adapt their metabolism to the requirements of their ecological niche
to avoid iron shortage as well as iron toxicity. Therefore, mechanisms have been evolved to …

Aspergillus fumigatus is the most common cause of invasive aspergillosis, a life-threatening
infection mainly affecting immunocompromised patients. The essential metals copper and …

Aspergillus fumigatus is able to invade and grow in the lungs of immunosuppressed
individuals and causes invasive pulmonary aspergillosis. The concentration of free zinc in …

Metal nanoparticles used as antifungals have increased the occurrence of fungal–metal
interactions. However, there is a lack of knowledge about how these interactions cause …

A spergillus fumigatus can invade the lungs of immunocompromised individuals causing a
life‐threatening disease called invasive pulmonary aspergillosis (IPA). To grow in the lungs …

In Aspergillus fumigatus, the regulation of zinc homeostasis is strongly influenced by
environmental pH. Thus, the study of zinc-regulated gene expression in A. fumigatus …

Relatively few transcription factors that govern the virulence of Aspergillus fumigatus are
known. We constructed 11 A. fumigatus transcription factor mutants and screened them for …

Cryptic links between apparently unrelated metabolic systems represent potential new drug
targets in fungi. Evidence of such a link between zinc and gliotoxin (GT) biosynthesis in …

The mold Aspergillus fumigatus employs two high-affinity uptake systems, reductive iron
assimilation (RIA) and siderophore-mediated iron acquisition (SIA), for the acquisition of the …