Functional characterization of genes encoding cadmium pumping P1B-type ATPases in Aspergillus fumigatus and Aspergillus nidulans
ABSTRACT Several P1B-type ATPases are important Cd2+/Cu2+ pumps in Aspergillus
species, and they are tightly associated with the heavy metal stress tolerance of these …
species, and they are tightly associated with the heavy metal stress tolerance of these …
[HTML][HTML] Copper at the fungal pathogen-host axis
S García-Santamarina, DJ Thiele - Journal of Biological Chemistry, 2015 - ASBMB
Fungal infections are responsible for millions of human deaths annually. Copper, an
essential but toxic trace element, plays an important role at the host-pathogen axis during …
essential but toxic trace element, plays an important role at the host-pathogen axis during …
[HTML][HTML] Pathogenic adaptations to host-derived antibacterial copper
KS Chaturvedi, JP Henderson - Frontiers in cellular and infection …, 2014 - frontiersin.org
Recent findings suggest that both host and pathogen manipulate copper content in infected
host niches during infections. In this review, we summarize recent developments that …
host niches during infections. In this review, we summarize recent developments that …
Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity
N Raffa, TH Won, A Sukowaty… - Proceedings of the …, 2021 - National Acad Sciences
The maintenance of sufficient but nontoxic pools of metal micronutrients is accomplished
through diverse homeostasis mechanisms in fungi. Siderophores play a well established …
through diverse homeostasis mechanisms in fungi. Siderophores play a well established …
Toxic metal/metalloid tolerance in fungi—a biotechnology-oriented approach
I Pócsi - Cellular effects of heavy metals, 2011 - Springer
This review aims at the biotechnological evaluation of the wealth of data accumulated in the
last decade on the molecular background of the toxic metal/metalloid tolerance of fungi …
last decade on the molecular background of the toxic metal/metalloid tolerance of fungi …
Identification of high-affinity copper transporters in Aspergillus fumigatus
YS Park, H Lian, M Chang, CM Kang… - Fungal Genetics and …, 2014 - Elsevier
We investigated the copper metabolism of Aspergillus fumigatus, which has not been
characterized well. We cloned the putative copper transporters ctrA 2 and ctrC from A …
characterized well. We cloned the putative copper transporters ctrA 2 and ctrC from A …
Linking calcium signaling and mitochondrial function in fungal drug resistance
P Bowyer, MJ Bromley… - Proceedings of the …, 2020 - National Acad Sciences
The host range for Aspergillus fumigatus is wide, including mammals, aves, and insecta
(stonebrood). This is linked to the significant adaptability of this important fungal pathogen. It …
(stonebrood). This is linked to the significant adaptability of this important fungal pathogen. It …
[HTML][HTML] Copper homeostasis at the host-pathogen interface
V Hodgkinson, MJ Petris - Journal of Biological Chemistry, 2012 - ASBMB
The trace element copper is indispensable for all aerobic life forms. Its ability to cycle
between two oxidation states, Cu 1+ and Cu 2+, has been harnessed by a wide array of …
between two oxidation states, Cu 1+ and Cu 2+, has been harnessed by a wide array of …
[HTML][HTML] Paths and determinants for Penicillium janthinellum to resist low and high copper
J Xu, GL Chen, XZ Sun, XW Fan, L You-Zhi - Scientific Reports, 2015 - nature.com
Copper (Cu) tolerance was well understood in fungi yeasts but not in filamentous fungi.
Filamentous fungi are eukaryotes but unlike eukaryotic fungi yeasts, which are a collection …
Filamentous fungi are eukaryotes but unlike eukaryotic fungi yeasts, which are a collection …
[HTML][HTML] Insights Into Histoplasma capsulatum Behavior on Zinc Deprivation
Histoplasma capsulatum is a thermodimorphic fungus that causes histoplasmosis, a mycosis
of global incidence. The disease is prevalent in temperate and tropical regions such as …
of global incidence. The disease is prevalent in temperate and tropical regions such as …