The Involvement of Oxidative Stress and Glutamate and Nitric Oxide Pathways on the Analgesic Effect of Genotropin in a Model of Peripheral Neuropathy

S Saffarpour, P Sadeghi-Tehran, A Mehraz… - Available at SSRN … - papers.ssrn.com
Purpose: Recent data suggests a potential role for genotropin or a recombinant human
growth hormone (GH) in pain modulation, homeostasis, and tissue repair after injury, as well …

The Relationship of Glutamate, Oxidative and Nitric Oxide Pathways in the Analgesic Effect of Growth Hormone in a Model of Peripheral Neuropathy

S Saffarpour, P Sadeghi Tehran… - Oxidative and Nitric Oxide … - papers.ssrn.com
Purpose:. Recent data suggested a potential action for Growth hormone (GH) in pain
modulation. It reported growth hormone treatment reduced the increased level of oxidative …

Neurotropin attenuates local inflammatory response and inhibits demyelination induced by chronic constriction injury of the mouse sciatic nerve

S Nishimoto, K Okada, H Tanaka, M Okamoto… - Biologicals, 2016 - Elsevier
Neuropathic pain caused by nerve damage in the central and/or peripheral nervous systems
is a refractory disorder and the management of such chronic pain has become a major …

[PDF][PDF] Role of neuropeptides and ginsenoside Rg1 in peripheral nerve injury-induced neuropathic pain in mice

S Kaur, A Muthuraman - EC Pharmacology an d Toxicology, 2020 - academia.edu
Ginsenoside Rg1 (GRg) is a natural bioactive flavonoid compound. It has potential action on
the neuronal system and it prevents the neurodegenerative disorders via alteration of …

Growth hormone releasing hormone reverses endotoxin-induced localized inflammatory hyperalgesia without reducing the upregulated cytokines, nerve growth factor …

RS Talhouk, NE Saadé, G Mouneimne… - Progress in Neuro …, 2004 - Elsevier
During inflammatory processes, the hypothalamic-pituitary axis is activated which can
subsequently result in analgesia. For example, hypothalamic corticotrophin-releasing …

Preventive effects of progesterone against neuropathic pain responses in a rat model of chronic constriction injury.

M Jarrahi, R Hasani, A Rashidy-Pour, HA Safakhah - 2019 - cabidigitallibrary.org
Introduction: Neuropathic pain is a chronic pain that results from damage to the central
nervous system and also environment. Neuropathic pain is important for general health and …

Preventive effects of progesterone on the electrophysiological response of sciatic nerve in the chronic constriction injury model of neuropathic pain in the rat.

M Jarrahi, HA Safakhah, R Hasani, A Rashidy_Pour - 2023 - cabidigitallibrary.org
Introduction: Peripheral neuropathy (PN) is resulted from damage to the peripheral nervous
system (PNS) and usually causes weakness, numbness, and neuropathic pain, which is a …

Neurotropin® ameliorates chronic pain associated with scar formation in a mouse model: A gene expression analysis of the inflammatory response

X Zhou, H Iida, Y Li, A Ota, L Zhuo… - Molecular …, 2024 - journals.sagepub.com
Background: Scar formation after trauma and surgery involves an inflammatory response
and can lead to the development of chronic pain. Neurotropin®(NTP) is a nonprotein extract …

Decreased GDNF mRNA expression in dorsal spinal cord of unilateral arthritic rat

M Fang, Y Wang, HX Liu, XS Liu, JS Han - Neuroreport, 2000 - journals.lww.com
It is now well established that nerve growth factor (NGF) plays a key role in inflammation-
induced hyperalgesia. It was also reported that brain derived neurotrophic factor (BDNF) …

Potential anxiolytic and antidepressant-like effects of luteolin in a chronic constriction injury rat model of neuropathic pain: Role of oxidative stress, neurotrophins, and …

T Mokhtari, M Lu, AEM El-Kenawy - International Immunopharmacology, 2023 - Elsevier
This study aimed to examine the effects of luteolin (LUT) on chronic neuropathic pain (NP)-
induced mood disorders (ie, anxiety and depression) by regulating oxidative stress …