[HTML][HTML] Inhibition of Different Pain Pathways Attenuates Oxidative Stress in Glial Cells: A Mechanistic View on Neuroprotective Effects of Different Types of Analgesics

MR Eskandari, P Eftekhari, S Abbaszadeh… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Neuropathic pain results from trauma or diseases affecting the central nervous system
(CNS) and triggers a cascade of events in different CNS parts that eventually lead to …

[HTML][HTML] The regulation of sGC on the rat model of neuropathic pain is mediated by 5-HT1ARs and NO/cGMP pathway

Z Xu, B Yang, J Zhang, J Zheng - American Journal of Translational …, 2016 - ncbi.nlm.nih.gov
Inadequate management of neuropathic pain results in poor clinical outcomes and reduces
quality of life for the patient all over the world, but intricate interplay between wide variety of …

Pharmacological activation of heme oxygenase (HO)-1/carbon monoxide pathway prevents the development of peripheral neuropathic pain in Wistar rats

KRV Bijjem, SSV Padi, P lal Sharma - Naunyn-Schmiedeberg's archives of …, 2013 - Springer
Recent studies have emphasized the contribution of neuroinflammation and oxido-
nitrosative stress to neuropathic pain. Both, heme oxygenase (HO)-1 and carbon monoxide …

Nerve growth factor governs the enhanced ability of opioids to suppress inflammatory pain

SA Mousa, BP Cheppudira, M Shaqura, O Fischer… - Brain, 2007 - academic.oup.com
Nerve growth factor (NGF) regulates sensory neuron phenotype by elevated expression of
ion channels and receptors contributing to pain. Peripheral opioid antinociception is …

Expression of central glucocorticoid receptors after peripheral nerve injury contributes to neuropathic pain behaviors in rats

S Wang, G Lim, Q Zeng, B Sung, Y Ai… - Journal of …, 2004 - Soc Neuroscience
Peripheral glucocorticoid receptors (GRs) play a significant role in the anti-inflammatory
effects of glucocorticoids; however, the role of central GRs in nociceptive behaviors after …

Exercise-induced improvement of neuropathic pain in rats: Possible role of oxidative stress

S Ghasemi, A Ghanbari, A Rashidy-pour… - Biomedical Research …, 2023 - biomedpress.org
Introduction: Neuropathic pain is one of the main problems that succeeds a lesion or
disease of the somatosensory system. In this study, the effect of exercise on oxidative stress …

Vitamin C enhances the analgesic effect of gabapentin on rats with neuropathic pain

R Li, L Shen, X Yu, C Ma, Y Huang - Life sciences, 2016 - Elsevier
Abstract Aims Gabapentin (Gap) relieves neuropathic pain, but it has several adverse effects
as well. We aimed to investigate whether vitamin C (VitC) supplementation would reduce the …

Go-sha-jinki-Gan (GJG) ameliorates allodynia in chronic constriction injury model mice via suppression of TNF-α expression in the spinal cord

M Nakanishi, A Nakae, Y Kishida, K Baba… - Molecular …, 2016 - journals.sagepub.com
Background Alternative medicine is noted for its clinical effect and minimal invasiveness in
the treatment of neuropathic pain. Go-sha-jinki-Gan, a traditional Japanese herbal medicine …

Distinct roles of neuregulin in different models of neuropathic pain

DW Dai, Z Xu, X Chen, L Yuan, AJ Zhang… - Neurological …, 2014 - Springer
The objective of the study was to investigate the role of neuregulin–ErbB signaling in
neuropathic pain in different types of injury. Neuregulin-1 (NRG-1) was injected into animals …

Progesterone prevents nerve injury-induced allodynia and spinal NMDA receptor upregulation in rats

MF Coronel, F Labombarda, P Roig, MJ Villar… - Pain …, 2011 - academic.oup.com
Background. Peripheral nerve injury-evoked neuropathic pain still remains a therapeutic
challenge. Recent studies support the notion that progesterone, a neuroactive steroid, may …