[HTML][HTML] An early granulocyte colony-stimulating factor treatment attenuates neuropathic pain through activation of mu opioid receptors on the injured nerve
MF Liao, SR Yeh, AL Lo, PK Chao, YL Lee, YH Hung… - Scientific reports, 2016 - nature.com
Several studies have shown that the mu opioid receptor (MOR) located in the peripheral
nerves can be activated after nerve injury and that it attenuates peripheral nociceptive …
nerves can be activated after nerve injury and that it attenuates peripheral nociceptive …
The oxidative response in the chronic constriction injury model of neuropathic pain
ECTH Tan, S Bahrami, AV Kozlov… - Journal of Surgical …, 2009 - Elsevier
BACKGROUND: In the chronic constriction injury model of rat neuropathic pain, oxidative
stress as well as antioxidants superoxide dismutase and reduced glutathione (GSH) are …
stress as well as antioxidants superoxide dismutase and reduced glutathione (GSH) are …
Glucocorticoid receptor inhibit the activity of NF-κB through p38 signaling pathway in spinal cord in the spared nerve injury rats
J Shao, R Xu, M Li, Q Zhao, X Ren, Z Li, J Cao, W Zang - Life sciences, 2018 - Elsevier
Abstract Aims The glucocorticoid receptors (GRs) are an active regulator in inflammatory
responses. The inflammatory reaction plays an important role in neuropathic pain, but the …
responses. The inflammatory reaction plays an important role in neuropathic pain, but the …
[HTML][HTML] Attenuation of SCI-Induced Hypersensitivity by Intensive Locomotor Training and Recombinant GABAergic Cells
S Jergova, EA Dugan, J Sagen - Bioengineering, 2023 - mdpi.com
The underlying mechanisms of spinal cord injury (SCI)-induced chronic pain involve
dysfunctional GABAergic signaling and enhanced NMDA signaling. Our previous studies …
dysfunctional GABAergic signaling and enhanced NMDA signaling. Our previous studies …
Progesterone reduces the expression of spinal cyclooxygenase‐2 and inducible nitric oxide synthase and prevents allodynia in a rat model of central neuropathic pain
MF Coronel, F Labombarda, AF De Nicola… - … journal of pain, 2014 - Wiley Online Library
Background Spinal cord injury (SCI) results in the development of chronic pain that is
refractory to conventional treatment. Progesterone, a neuroprotective steroid, may offer a …
refractory to conventional treatment. Progesterone, a neuroprotective steroid, may offer a …
[HTML][HTML] Gastrodin inhibits allodynia and hyperalgesia in painful diabetic neuropathy rats by decreasing excitability of nociceptive primary sensory neurons
W Sun, B Miao, XC Wang, JH Duan, X Ye, WJ Han… - PLoS one, 2012 - journals.plos.org
Painful diabetic neuropathy (PDN) is a common complication of diabetes mellitus and
adversely affects the patients' quality of life. Evidence has accumulated that PDN is …
adversely affects the patients' quality of life. Evidence has accumulated that PDN is …
The antioxidant N-(2-mercaptopropionyl)-glycine (tiopronin) attenuates expression of neuropathic allodynia and hyperalgesia
M Shahid, F Subhan, NU Islam, N Ahmad… - Naunyn-Schmiedeberg's …, 2021 - Springer
The current pharmacotherapy of neuropathic pain is inadequate as neuropathic pain
involves varied clinical manifestations with multifactorial etiology, modulated by a cascade of …
involves varied clinical manifestations with multifactorial etiology, modulated by a cascade of …
The role of angiotensin receptors in neuropathic pain
N Kalynovska - 2012 - dspace.cuni.cz
Neuropathic pain is one of the most debilitating disorders. Currently available treatments for
neuropathic pain are still unsatisfactory as they have only limited treatment effect and …
neuropathic pain are still unsatisfactory as they have only limited treatment effect and …
[PDF][PDF] The different dynamic changes of nerve growth factor in the dorsal horn and dorsal root ganglion leads to hyperalgesia and allodynia in diabetic neuropathic …
Z Gao, Y Feng, H Ju - Pain physician, 2017 - painphysicianjournal.com
Background: Diabetic peripheral neuropathy (DPN) is the most common complication of
diabetes and more than half of the patients with DPN have self-reported symptoms referring …
diabetes and more than half of the patients with DPN have self-reported symptoms referring …
[HTML][HTML] The refined biomimetic NeuroDigm GEL™ model of neuropathic pain in a mature rat
MR Hannaman, DA Fitts, RM Doss, DE Weinstein… - …, 2016 - ncbi.nlm.nih.gov
Background: Many humans suffering with chronic neuropathic pain have no objective
evidence of an etiological lesion or disease. Frequently their persistent pain occurs after the …
evidence of an etiological lesion or disease. Frequently their persistent pain occurs after the …