A significant clinical need exists to differentiate human pluripotent stem cells (hPSCs) into
cardiomyocytes, enabling tissue modeling for in vitro discovery of new drugs or cell-based …

Cardiomyocytes derived from human embryonic stem cells (hESC-CMs) are regarded as a
promising source for regenerative medicine, drug testing and disease modeling …

While adult heart muscle is the least regenerative of tissues, embryonic cardiomyocytes are
proliferative, with embryonic stem (ES) cells providing an endless reservoir. In addition to …

Tissue engineering aims at recapitulating permissive conditions that enable cells to
collaborate and form functional tissues. Applications range from human tissue modeling for …

Mechanical loading plays a critical role in cardiac pathophysiology. Engineered heart
tissues derived from human induced pluripotent stem cells (iPSCs) allow rigorous …

Cardiomyocytes from human pluripotent stem cells (hPSC-CM) have many potential
applications in disease modelling and drug target discovery but their phenotypic similarity to …

Human pluripotent stem cell (hPSC‐) derived cardiomyocytes have potential applications in
drug discovery, toxicity testing, developmental studies, and regenerative medicine. Before …

Systematically tunable in vitro platforms are invaluable in gaining insight to stem cell–
microenvironment interactions in three-dimensional cultures. Utilizing recombinant protein …

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) can be utilized to
understand the mechanisms underlying the development and progression of heart disease …

Pluripotent stem cells (PSCs), including embryonic stem cells (ESCs) and induced
pluripotent stem cells (iPSCs) have promise in regenerative medicine for a variety of …