Early-life adversity increases the vulnerability to develop psychopathologies and cognitive
decline later in life. This association is supported by clinical and preclinical studies …

Early life is a period of unique sensitivity during which experience can confer enduring
effects on brain structure and function. During early perinatal life the quality of the …

While the detrimental impact of inflammation on adult hippocampal neurogenesis and
associated behaviors has recently gained credence, the effects of inflammation on the …

Early-life stress lastingly affects adult cognition and increases vulnerability to
psychopathology, but the underlying mechanisms remain elusive. In this Opinion article, we …

Early life stress (ES) increases vulnerability to psychopathology and impairs cognition in
adulthood. These ES‐induced deficits are associated with lasting changes in hippocampal …

Adverse early life experience decreases adult hippocampal neurogenesis and results in
increased vulnerability to neuropsychiatric disorders. Despite that the effects of postnatal …

During the perinatal period, the brain undergoes substantial structural changes, synaptic
rearrangements, and development of neuronal circuits which ultimately determine brain …

Whereas genetic factors contribute crucially to brain function, early-life events, including
stress, exert long-lasting influence on neuronal function. Here, we focus on the …

Exposure to adversity and stress early in development yields vulnerability to mental
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …

Adverse experiences early in life are associated with the development of psychiatric
illnesses. The hippocampus is likely to play pivotal role in generating these effects: it …