The interplay of early-life stress, nutrition, and immune activation programs adult hippocampal structure and function
L Hoeijmakers, PJ Lucassen, A Korosi - Frontiers in molecular …, 2015 - frontiersin.org
Early-life adversity increases the vulnerability to develop psychopathologies and cognitive
decline later in life. This association is supported by clinical and preclinical studies …
decline later in life. This association is supported by clinical and preclinical studies …
Early-life stress mediated modulation of adult neurogenesis and behavior
A Korosi, EFG Naninck, CA Oomen, M Schouten… - Behavioural brain …, 2012 - Elsevier
Early life is a period of unique sensitivity during which experience can confer enduring
effects on brain structure and function. During early perinatal life the quality of the …
effects on brain structure and function. During early perinatal life the quality of the …
Inflammation and the developing brain: consequences for hippocampal neurogenesis and behavior
HF Green, YM Nolan - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
While the detrimental impact of inflammation on adult hippocampal neurogenesis and
associated behaviors has recently gained credence, the effects of inflammation on the …
associated behaviors has recently gained credence, the effects of inflammation on the …
Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics
Early-life stress lastingly affects adult cognition and increases vulnerability to
psychopathology, but the underlying mechanisms remain elusive. In this Opinion article, we …
psychopathology, but the underlying mechanisms remain elusive. In this Opinion article, we …
Chronic early life stress alters developmental and adult neurogenesis and impairs cognitive function in mice
EFG Naninck, L Hoeijmakers… - …, 2015 - Wiley Online Library
Early life stress (ES) increases vulnerability to psychopathology and impairs cognition in
adulthood. These ES‐induced deficits are associated with lasting changes in hippocampal …
adulthood. These ES‐induced deficits are associated with lasting changes in hippocampal …
Early life stress and hippocampal neurogenesis in the neonate: sexual dimorphism, long term consequences and possible mediators
N Lajud, L Torner - Frontiers in molecular neuroscience, 2015 - frontiersin.org
Adverse early life experience decreases adult hippocampal neurogenesis and results in
increased vulnerability to neuropsychiatric disorders. Despite that the effects of postnatal …
increased vulnerability to neuropsychiatric disorders. Despite that the effects of postnatal …
Long-lasting consequences of early life stress on brain structure, emotion and cognition
HJ Krugers, M Joëls - Behavioral neurobiology of stress-related disorders, 2014 - Springer
During the perinatal period, the brain undergoes substantial structural changes, synaptic
rearrangements, and development of neuronal circuits which ultimately determine brain …
rearrangements, and development of neuronal circuits which ultimately determine brain …
Hippocampal neuroplasticity induced by early-life stress: functional and molecular aspects
KA Fenoglio, KL Brunson, TZ Baram - Frontiers in neuroendocrinology, 2006 - Elsevier
Whereas genetic factors contribute crucially to brain function, early-life events, including
stress, exert long-lasting influence on neuronal function. Here, we focus on the …
stress, exert long-lasting influence on neuronal function. Here, we focus on the …
[HTML][HTML] Broken or maladaptive? Altered trajectories in neuroinflammation and behavior after early life adversity
P Ganguly, HC Brenhouse - Developmental cognitive neuroscience, 2015 - Elsevier
Exposure to adversity and stress early in development yields vulnerability to mental
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …
Environmental enrichment rescues survival and function of adult-born neurons following early life stress
L Rule, J Yang, H Watkin, J Hall, NM Brydges - Molecular Psychiatry, 2021 - nature.com
Adverse experiences early in life are associated with the development of psychiatric
illnesses. The hippocampus is likely to play pivotal role in generating these effects: it …
illnesses. The hippocampus is likely to play pivotal role in generating these effects: it …