New perspectives on chronic obstructive pulmonary disease
BR Celli, D Singh, C Vogelmeier… - International Journal of …, 2022 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide; many recent advances have been made in many aspects of the disease. The aim …
worldwide; many recent advances have been made in many aspects of the disease. The aim …
[HTML][HTML] Blood eosinophil levels as a biomarker in COPD
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disorder and patients
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …
respond differently to treatment. Blood eosinophils are a potential biomarker to stratify …
Global strategy for the diagnosis, management, and prevention of chronic obstructive lung disease: the GOLD science committee report 2019
Precision medicine is a patient-specific approach that integrates all relevant clinical, genetic
and biological information in order to optimise the therapeutic benefit relative to the …
and biological information in order to optimise the therapeutic benefit relative to the …
Blood eosinophil count-guided corticosteroid therapy and as a prognostic biomarker of exacerbations of chronic obstructive pulmonary disease: a systematic review …
T Liu, ZJ Xiang, XM Hou, JJ Chai… - … in Chronic Disease, 2021 - journals.sagepub.com
Background: Chronic obstructive pulmonary disease (COPD) is characterized by persistent
respiratory symptoms and dyspnea, as well as an increase in the number of leukocytes in …
respiratory symptoms and dyspnea, as well as an increase in the number of leukocytes in …
Pharmacological treatment of stable chronic obstructive pulmonary disease
D Singh - Respirology, 2021 - Wiley Online Library
Pharmacological treatment for chronic obstructive pulmonary disease (COPD) aims to
alleviate symptoms and reduce the future risk of events such as exacerbations, disease …
alleviate symptoms and reduce the future risk of events such as exacerbations, disease …
Blood eosinophil count: a biomarker of an important treatable trait in patients with airway disease
Inhaled corticosteroids (ICS) are widely used to treat patients with chronic obstructive
pulmonary disease (COPD). Their main impact is to reduce the risk of exacerbations; in …
pulmonary disease (COPD). Their main impact is to reduce the risk of exacerbations; in …
Blood eosinophils as a marker of response to inhaled corticosteroids in COPD
NC Barnes, R Sharma, S Lettis… - European Respiratory …, 2016 - Eur Respiratory Soc
Identification of a biomarker that predicts response to inhaled corticosteroids (ICS) would
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …
help evaluate the risk/benefit profile of ICS in chronic obstructive pulmonary disease (COPD) …
Shall we focus on the eosinophil to guide treatment with systemic corticosteroids during acute exacerbations of COPD?: PRO
J Camp, JL Cane, M Bafadhel - Medical Sciences, 2018 - mdpi.com
In an era of precision medicine, it seems regressive that we do not use stratified approaches
to direct treatment of oral corticosteroids during an exacerbation of chronic obstructive …
to direct treatment of oral corticosteroids during an exacerbation of chronic obstructive …
Blood eosinophils as a biomarker of future COPD exacerbation risk: pooled data from 11 clinical trials
D Singh, JA Wedzicha, S Siddiqui, A de la Hoz… - Respiratory …, 2020 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterised by progressive
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which …
In 'real world'patients with COPD, exacerbation history, and not blood eosinophils, is the most reliable predictor of future exacerbations
H Worth, R Buhl, CP Criée, P Kardos, E Gückel… - Respiratory …, 2023 - Springer
Introduction There is an interest in the role of blood eosinophils for predicting inhaled
corticosteroid (ICS) response in chronic obstructive pulmonary disease (COPD). Most data …
corticosteroid (ICS) response in chronic obstructive pulmonary disease (COPD). Most data …