Collagen XVII (COL17) participates in keratinocyte adhesion and possibly migration, as
COL17 defects disrupt keratinocyte-basal lamina adhesion and underlie the disease non …

Collagen XVII is a hemidesmosomal anchorage molecule of basal keratinocytes that
promotes stable epidermal-dermal adhesion. One unique feature of collagen XVII is that its …

The epidermis is the outer covering of the skin and provides a protective interface between
the body and the environment. It is well established that the epidermis is maintained by stem …

Engineered biomatrices offer the potential to recapitulate the regenerative
microenvironment, with important implications in tissue repair. In this context, investigation of …

Interfollicular epidermal stem cells (IFE-SCs) have self-renewal and differentiation
potentials, and maintain epidermal homeostasis. Stem cells in vivo are regulated by the …

The wound healing process relies on the proper execution and regulation of signaling
pathways and transcriptional regulators to properly coordinate the wound healing response …

Stratified epithelia are made up of several layers of cells, which act as a protective barrier for
the organ they cover. To ensure their shielding effect, epithelia are naturally able to cope …

Within the epidermis and dermis of the skin, cells secrete and are surrounded by the
extracellular matrix (ECM), which provides structural and biochemical support. The ECM of …

In skin wounds, the chemokine CXCR3 receptor appears to play a key role in coordinating
the switch from regeneration of the ontogenically distinct mesenchymal and epithelial …

The epidermis and skin appendages are maintained by their resident epithelial stem cells,
which undergo long‐term self‐renewal and multilineage differentiation. Upon injury, stem …