[PDF][PDF] Design and development of a hydrogel formulation with nanoparticles for the treatment of glioblastoma multiforme

LEC dos Santos - 2021 - tara.tcd.ie
Glioblastoma multiforme (GBM) is the most aggressive form of brain tumours. GBM treatment
is challenging because tumours are highly invasive and it is difficult to achieve effective …

[HTML][HTML] Biocompatible copolymer formulations to treat glioblastoma multiforme

LCS Erthal, OL Gobbo, E Ruiz-Hernandez - Acta biomaterialia, 2021 - Elsevier
The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years
while the prognosis for the patients is still poor and most of them survive less than 1 year …

Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: An approach for a local therapy of glioblastoma multiforme

LCS Erthal, Y Shi, KJ Sweeney, OL Gobbo… - Scientific Reports, 2023 - nature.com
Malignant gliomas are a type of primary brain tumour that originates in glial cells. Among
them, glioblastoma multiforme (GBM) is the most common and the most aggressive brain …

Hydrogel-Based Drug Delivery Nanosystems for the Treatment of Brain Tumors: A Systematic Review

S Kumar, P Kumari, D Suthar, RR Raj, A Jain - Journal for Research in …, 2024 - jrasb.com
The limitations and negative effects of current therapeutic techniques for brain tumors
necessitate the selection of alternative therapeutic options. Therapeutic hydrogel systems …

Advances in Hydrogels of Drug Delivery Systems for the Local Treatment of Brain Tumors

J Yang, Z Wang, C Ma, H Tang, H Hao, M Li, X Luo… - Gels, 2024 - mdpi.com
The management of brain tumors presents numerous challenges, despite the employment of
multimodal therapies including surgical intervention, radiotherapy, chemotherapy, and …

Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma

C Bastiancich, P Danhier, V Préat, F Danhier - Journal of Controlled …, 2016 - Elsevier
Among central nervous system tumors, Glioblastoma (GBM) is the most common, aggressive
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …

Hydrogel-based drug delivery nanosystems for the treatment of brain tumors

J Basso, A Miranda, S Nunes, T Cova, J Sousa… - Gels, 2018 - mdpi.com
Chemotherapy is commonly associated with limited effectiveness and unwanted side effects
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …

[PDF][PDF] Development of innovative nanocomposite hydrogels for the treatment of Glioblastoma Multiforme

A Djoudi, R Molina-Peña, N Buchtová, S Avril, L Sindji… - nanoinnovation2021.eu
Glioblastoma multiforme (GBM) is a high recidivism and mortality characterized subtype of
gliomas. According to the WHO, it belongs to the Grade IV brain cancers. It is highly invasive …

An injectable in situ hydrogel platform for sustained drug release against glioblastoma

W Yue, T Wang, L Xie, J Shen - Journal of Drug Delivery Science and …, 2024 - Elsevier
Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults.
Despite aggressive surgical and medical treatments, the prognosis for patients with GBM …

Local delivery to malignant brain tumors: Potential biomaterial-based therapeutic/adjuvant strategies

M Alghamdi, M Gumbleton, B Newland - Biomaterials Science, 2021 - pubs.rsc.org
Glioblastoma (GBM) is the most aggressive malignant brain tumor and is associated with a
very poor prognosis. The standard treatment for newly diagnosed patients involves total …