Background Chronic hepatitis B virus (HBV) infection is characterized by the presence of
dysfunctional exhausted CD8+ T cells that hamper viral control. We investigated the …

Background & Aims The role of hepatitis B virus (HBV)-specific CD4 T cells in patients with
chronic HBV infection is not clear. Thus, we aimed to elucidate this in patients with chronic …

In this study, we aimed to detect and characterize ex vivo virus-specific CD8+ T cells in
patients with immune-tolerant hepatitis B virus (HBV) infection. We investigated a Korean …

Background Patients with resolved hepatitis B virus (HBV) infection undergoing
chemotherapy or immunosuppressive therapy are potentially at risk of HBV reactivation …

Patients with chronic HBV infection show poor immune response to HBV-specific CD8+ T
cells. Several studies demonstrate that regulatory T cells (Treg) and dendritic cells (DC) are …

Objective To investigate the difference of peripheral blood T-lymphocyte subsets in patients
with chronic hepatitis B and asymptomatic HBV carriers, and to analyze the relationship …

The impaired T cell responses observed in chronic hepatitis B (HBV) patients are
considered to contribute to the chronicity of the infection. Research on this impairment has …

Hepatitis B virus (HBV) infection significantly impacts Asian populations. The influences of
continuous HBV antigen and inflammatory stimulation to T cells in chronic hepatitis B (CHB) …

AIM: To characterize the peripheral T-cell subpopulation profiles and their correlation with
hepatitis B virus (HBV) replication in different clinical stages of chronic HBV infection …

Background Chronic hepatitis B virus (HBV) infection includes a set of heterogeneous
clinical patterns, and core-protein-specific T cell response is important for virus control and …