To clarify the characteristics of TCR αβ T cells in the peripheral blood of patients with chronic
hepatitis B (CHB), we investigated the patterns of Complementarity Determining Region3 …

Background The roles of CD4+ CD25+ regulatory T cells (Treg) in chronicity of hepatitis B
virus (HBV) infection have been confirmed. We aimed to explore alteration of Treg in …

B cell-mediated humoral immunity plays a vital role in viral infections, including chronic
hepatitis B virus (HBV) infection, which remains a critical global public health issue. Despite …

Dysfunctional CD8+ T cells present in chronic virus infections can express programmed
death 1 (PD-1) molecules, and the inhibition of the engagement of PD-1 with its ligand (PD …

Treatment options for chronic hepatitis B (CHB) infection are extremely limited. CXCR5+
CD8+ T cell is a novel cell subtype and could possess strong cytotoxic properties in HIV …

CD4+ T cells serve as master regulators of the adaptive immune response to HBV. However,
CD4+ T‐cell subsets are heterogeneous, and it remains unknown how the antiviral agents …

Background: Hepatitis B is an immune response-mediated disease. The aim of this study
was to explore the differences of ratios of T-helper (Th) 2 cells to Th1 cells and cytokine …

Aim This study was designed to investigate the levels of circulating regulatory T cells
(Tregs), and their functional subpopulations and related cytokines in chronic hepatitis B …

Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infection are global health
problems affecting 600 million people worldwide. Indeed, HBV and HCV are hepatotropic …

To assess the significance of cell-mediated immunity, T cells were derived from the
peripheral blood and liver tissue of hepatitis B virus (HBV)-infected patients and controls …