Aims/hypothesis Development of type 2 diabetes depends on environmental and genetic
factors. We investigated the epigenome-wide association of prevalent diabetes with DNA …

Summary Background Indian Asians, who make up a quarter of the world's population, are
at high risk of developing type 2 diabetes. We investigated whether DNA methylation is …

Background Type 2 diabetes mellitus (T2D) is highly prevalent in Middle-Eastern and North
African Arab populations, but the molecular basis for this susceptibility is unknown. Altered …

In the last years, epigenetic processes have emerged as a promising area of complex
diseases research. DNA methylation measured in Long Interspersed Nucleotide Element 1 …

Several studies have investigated the relationship between genetic variation and DNA
methylation with respect to type 2 diabetes, but it is unknown if DNA methylation is a …

Inter-individual DNA methylation variations were frequently hypothesized to alter individual
susceptibility to Type 2 Diabetes Mellitus (T2DM). Sequence-influenced methylations were …

Abstract Background Type 2 diabetes (T2D) is a heterogeneous disease with well-known
genetic and environmental risk factors contributing to its prevalence. Epigenetic …

Aims/hypothesis Tobacco smoking, a risk factor for diabetes, is an established modifier of
DNA methylation. We hypothesised that tobacco smoking modifies DNA methylation of …

DNA methylation (DNAm) has been found to show robust and widespread age-related
changes across the genome. DNAm profiles from whole blood can be used to predict human …

Abstract Background Type 2 diabetes (T2D) is a multifactorial, polygenic disease caused by
impaired insulin secretion and insulin resistance. Genome-wide association studies (GWAS) …