Phosphorus, an indispensable nutrient, plays an essential role in cell composition,
metabolism, and signal transduction. When inorganic phosphorus (Pi) is scarce, the Pi …

Escherichia coli have developed one of the most efficient regulatory response mechanisms
to phosphate starvation. The machinery involves a cascade with a two-component system …

Phosphorus is one of the most important macronutrients and is indispensable for all
organisms as a critical structural component as well as participating in intracellular …

The bacteria E. coli have developed one of the most efficient regulatory response to
phosphate starvation that is known in detail. Achieving a mechanistic understanding of this …

Background E. coli can be used as bacterial cell factories for production of biofuels and
other useful compounds. The efficient production of the desired products requires careful …

Phosphorus (P) is an essential constituent in all types of living organisms. Bacteria, which
use inorganic phosphate (P i), as the preferred P source, have evolved complex systems to …

One of the most important achievements of bacteria is its capability to adapt to the changing
conditions of the environment. The competition for nutrients with other microorganisms …

ABSTRACT Inorganic orthophosphate (Pi, PO4 3−) is the preferred phosphorus (P) source
of most living cells. In enteric bacterial species such as Salmonella enterica serovar …

Recent reports support the long-standing hypothesis that acetyl phosphate, a physiologically
relevant small molecule, can serve as a phosphoryl donor to a subset of two-component …

This review concerns how Escherichia coli detects environmental inorganic orthophosphate
(Pi) to regulate genes of the phosphate (Pho) regulon by the PhoR/PhoB two-component …