[HTML][HTML] Abuse liability assessment of eslicarbazepine acetate in healthy male and female recreational sedative users: a phase I randomized controlled trial

N Levy-Cooperman, KA Schoedel, B Chakraborty… - Epilepsy & Behavior, 2016 - Elsevier
Rationale Eslicarbazepine acetate (ESL) is a once-daily oral antiepileptic drug for the
treatment of partial-onset seizures. Adverse events such as dizziness and somnolence …

Eslicarbazepine acetate: a double‐blind, add‐on, placebo‐controlled exploratory trial in adult patients with partial‐onset seizures

C Elger, M Bialer, JA Cramer, J Maia, L Almeida… - …, 2007 - Wiley Online Library
Objective: To explore the efficacy and safety of eslicarbazepine acetate (BIA 2‐093), a new
antiepileptic drug, as adjunctive therapy in adult patients with partial epilepsy. Methods: A …

Safety and efficacy of eslicarbazepine acetate (Zebinix) in everyday clinical practice using a retrospective multicentre audit

S Keogh, P McDonald, C Lawthom… - Journal of the …, 2013 - jns-journal.com
Background/Objective: We report on the safety and efficacy of Eslicarbazepine acetate (ESL)
in routine clinical practice. Method: A retrospective multicentre audit of outcomes following …

[HTML][HTML] Influence of titration schedule and maintenance dose on the tolerability of adjunctive eslicarbazepine acetate: An integrated analysis of three randomized …

G Krauss, V Biton, JH Harvey, C Elger, E Trinka… - Epilepsy Research, 2018 - Elsevier
Objective To examine the influence of titration schedule and maintenance dose on the
incidence and type of treatment-emergent adverse events (TEAEs) associated with …

[引用][C] A review of eslicarbazepine acetate (Stedesa®)

C Price, M Ryan - Mental Health Clinician, 2012 - meridian.allenpress.com
Eslicarbazepine acetate is an anticonvulsant medication approved in Europe for adjunctive
therapy in adults with partial-onset seizures. FDA approval is expected shortly for use in the …

Eslicarbazepine acetate

M Bialer, C Elger - The Treatment of Epilepsy, 2015 - Wiley Online Library
Eslicarbazepine acetate (ESL) is a voltage‐gated sodium and calcium channel blocker that
was identified as a promising candidate for clinical development in epilepsy through a drug …

[引用][C] Pharmacokinetic interaction between eslicarbazepine acetate and lamotrigine in healthy subjects

T Nunes, J Maia, L Almeida, P Soares-da-Silva - Epilepsia, 2007

Differences in hydrolase activities in the liver and small intestine between marmosets and humans

S Honda, T Fukami, K Hirosawa, T Tsujiguchi… - Drug Metabolism and …, 2021 - ASPET
For drug development, species differences in drug-metabolism reactions present obstacles
for predicting pharmacokinetics in humans. We characterized the species differences in …

Enantioselective assay for therapeutic drug monitoring of eslicarbazepine acetate: no interference with carbamazepine and its metabolites

G Alves, A Fortuna, J Sousa, R Direito… - Therapeutic drug …, 2010 - journals.lww.com
As add-on therapy, phase III clinical trials of eslicarbazepine acetate (ESL) conducted in
patients with refractory partial-onset seizures have shown good efficacy, safety, and …

Assessing the Effectiveness of Eslicarbazepine Acetate in Reducing Audiogenic Reflex Seizures in the GASH/Sal Model of Epilepsy

J Gonçalves-Sánchez, T Ramírez-Santos, DE López… - Biomedicines, 2024 - mdpi.com
Eslicarbazepine acetate (ESL) is a third-generation antiepileptic drug indicated as
monotherapy for adults with newly diagnosed epilepsy and as adjunctive therapy for the …