[PDF][PDF] An Investigation of the Charge Effects on the Uptake and Release Capacity of Mesoporous Silica Nanoparticles as Vehicles for Short Oligonucleotides

R Badihi, A Mahmoudi, MR Sazegar… - Journal of Applied …, 2024 - journals.iau.ir
An easy and cost-effective sol-gel procedure is described for the synthesis and co-
modification of mesoporous silica nanoparticles (MSNs) with various metal ions and positive …

A study on co-modification of MSNs with some transition metals and polyethyleneimine (PEI) as a versatile strategy for efficient delivery of short oligonucleotides

R Badihi, A Mahmoudi, MR Sazegar, K Nazari - Chemical Papers, 2022 - Springer
In this research, mesoporous silica nanoparticles (MSNs) were synthesized and
hydrothermally modified with different transition metals, including Co2+, Fe2+, and Zn2+ …

[HTML][HTML] Characterization of modified mesoporous silica nanoparticles as vectors for siRNA delivery

A Slita, A Egorova, E Casals, A Kiselev… - Asian journal of …, 2018 - Elsevier
Gene therapy using siRNA molecules is nowadays considered as a promising approach.
For successful therapy, development of a stable and reliable vector for siRNA is crucial. Non …

Mesoporous Silica Nanoparticles Decorated with Carbosilane Dendrons as New Non‐viral Oligonucleotide Delivery Carriers

Á Martínez, E Fuentes‐Paniagua… - … A European Journal, 2015 - Wiley Online Library
A novel nanosystem based on mesoporous silica nanoparticles covered with carbosilane
dendrons grafted on the external surface of the nanoparticles is reported. This system is able …

Enhanced gene delivery by polyethyleneimine coated mesoporous silica nanoparticles

H Zarei, R Kazemi Oskuee… - Pharmaceutical …, 2019 - Taylor & Francis
Due to large surface area, tunable pore size, easy surface manipulation, and low-toxicity
mesoporous silica nanoparticles (MSNs) may act as a suitable vector for gene delivery. In …

Mesoporous silica nanoparticles for enhancing the delivery efficiency of immunostimulatory DNA drugs

C Tao, Y Zhu, Y Xu, M Zhu, H Morita… - Dalton Transactions, 2014 - pubs.rsc.org
We developed a potential immunostimulatory double-stranded DNA (dsDNA) delivery
system by the binding of dsDNA to amino-modified mesoporous silica nanoparticles (MSNs) …

Functionalized large pore mesoporous silica nanoparticles for gene delivery featuring controlled release and co-delivery

SB Hartono, NT Phuoc, M Yu, Z Jia… - Journal of Materials …, 2014 - pubs.rsc.org
Novel mesoporous silica nanoparticles (LPMSNs) functionalised with degradable poly (2-
dimethylaminoethyl acrylate)(PDMAEA) have been developed (PDMAEA–LPMSNs) as …

Integrated hollow mesoporous silica nanoparticles for target drug/siRNA co‐delivery

X Ma, Y Zhao, KW Ng, Y Zhao - Chemistry–A European …, 2013 - Wiley Online Library
A hollow mesoporous silica nanoparticle (HMSNP) based drug/siRNA co‐delivery system
was designed and fabricated, aiming at overcoming multidrug resistance (MDR) in cancer …

[PDF][PDF] Preparation and characterization of mesoporous silica nanoparticles with enlarged pores capped with crosslinked PEI

L Sun, Y Liu, Z Yang, X Qi - J. Chinese Pharm. Sci., 2015 - researchgate.net
The epidemiological statistics reveals the striking patterns of cancer in women and
highlights the need for novel therapeutic strategies. In this work, mesoporous silica …

Enhanced gene and siRNA delivery by polycation-modified mesoporous silica nanoparticles loaded with chloroquine

SR Bhattarai, E Muthuswamy, A Wani… - Pharmaceutical …, 2010 - Springer
Purpose To prepare mesoporous silica-based delivery systems capable of simultaneous
delivery of drugs and nucleic acids. Methods The surface of mesoporous silica nanoparticles …