Packaging enough genetic materials is necessary for gene delivery, but functional
modification of the carriers may affect their gene loading capacity. In this study, RGD peptide …

Cancer remains a major global health challenge. Traditional chemotherapy often results in
side effects and drug resistance, necessitating the development of alternative treatment …

Mesoporous silica nanoparticles (MSNs) with large surface area, tunable pore size, and low
toxicity can act as suitable vehicles for drug and gene delivery. An MSN/DNA/PEI complex …

Organic-inorganic hybrid silica nanoparticles (PM-1, PM-2 and PM-3) with positive surface
charge and size below 200 nm were one-pot prepared viaMichael addition between 3 …

Cancer remains a major global health challenge. Traditional chemotherapy often results in
side effects and drug resistance, necessitating the development of alternative treatment …

An efficient enzyme-responsive controlled release carrier system was successfully
fabricated using single-stranded DNA encapsulated functional mesoporous silica …

Silica nanoparticles with controlled diameter (∼ 70− 300 nm) and with uniform pores of 20
nm are prepared by a low temperature (10° C) synthetic method in the presence of a dual …

General techniques: Powder X-ray diffraction (PXRD) and thermogravimetric analysis (TGA),
elemental analysis, transmission electron microscopy (TEM), N2 adsorption-desorption, UV …

Nanomaterials have been extensively used for the delivery of nucleic acids. This is attributed
to the unique features of nanoparticles to carry genetic material with different …

Nucleic acids, including DNA, microRNA (miRNA), small interfering RNA (siRNA), and
antisense oligonucleotide (ASO), are powerful gene regulators, which have been …