[HTML][HTML] Particle-size-dependent delivery of antitumoral miRNA using targeted mesoporous silica nanoparticles

L Haddick, W Zhang, S Reinhard, K Möller, H Engelke… - Pharmaceutics, 2020 - mdpi.com
Multifunctional core-shell mesoporous silica nanoparticles (MSN) were tailored in size
ranging from 60 to 160 nm as delivery agents for antitumoral microRNA (miRNA). The …

Ultra-small mesoporous silica nanoparticles as efficient carriers for pH responsive releases of anti-cancer drugs

H Zheng, CW Tai, J Su, X Zou, F Gao - Dalton Transactions, 2015 - pubs.rsc.org
Mesoporous silica has emerged as one of the most promising carriers for drug delivery
systems. However, the synthesis of ultra-small mesoporous silica nanoparticles (UMSNs) …

Aptamer-modified chitosan-capped mesoporous silica nanoparticles for co-delivery of cytarabine and daunorubicin in leukemia

SR Heydari, MH Ghahremani, F Atyabi… - International Journal of …, 2023 - Elsevier
In this study, surface modified mesoporous silica nanoparticles (MSNs) were prepared for
the targeted delivery of the anticancer agents, daunorubicin (DNR) and cytarabine (CTR) …

Hollow Mesoporous Silica/Poly(l-lysine) Particles for Codelivery of Drug and Gene with Enzyme-Triggered Release Property

Y Zhu, W Meng, H Gao, N Hanagata - The Journal of Physical …, 2011 - ACS Publications
We designed, for the first time, an enzyme-triggered drug and gene codelivery system
combining hollow mesoporous silica (HMS) with enzyme degradable poly (l-lysine)(PLL) …

Facile synthesis of monodispersed mesoporous silica nanoparticles with ultralarge pores and their application in gene delivery

MH Kim, HK Na, YK Kim, SR Ryoo, HS Cho, KE Lee… - ACS …, 2011 - ACS Publications
Among various nanoparticles, the silica nanoparticle (SiNP) is an attractive candidate as a
gene delivery carrier due to advantages such as availability in porous forms for …

[PDF][PDF] Mesoporous Silica Nanoparticles as Versatile carrier platforms in therapeutic applications

Z Jafari, S Honarmand, F Rahimi, A Akbari… - J Nanosci …, 2021 - researchgate.net
The utilization of nanotechnology is one of the fast-growing scientific discoveries that
significantly affect our daily lives, especially its application in nanomedicine and targeted …

[HTML][HTML] siRNA delivery using intelligent chitosan-capped mesoporous silica nanoparticles for overcoming multidrug resistance in malignant carcinoma cells

R Heidari, P Khosravian, SA Mirzaei, F Elahian - Scientific reports, 2021 - nature.com
Although siRNA is a promising technology for cancer gene therapy, effective cytoplasmic
delivery has remained a significant challenge. In this paper, a potent siRNA transfer system …

Intracellular delivery of antisense peptide nucleic acid by fluorescent mesoporous silica nanoparticles

X Ma, G Devi, Q Qu, DFK Toh, G Chen… - Bioconjugate …, 2014 - ACS Publications
In order to overcome poor cell permeability of antisense peptide nucleic acid (PNA), a
fluorescent mesoporous silica nanoparticle (MSNP) carrier was developed to successfully …

Mesoporous Silica Nanoparticles for Efficient siRNA Delivery

M Tarannum, JL Vivero-Escoto - RNA Nanotechnology and …, 2022 - taylorfrancis.com
Mesoporous silica nanoparticles (MSNs) are inorganic materials with a highly ordered
network of pores within a silicon oxide framework. This chapter focuses on describing the …

An approach to prepare polyethylenimine functionalized silica-based spheres with small size for siRNA delivery

M Yu, Y Niu, Y Yang, SB Hartono, J Yang… - … Applied Materials & …, 2014 - ACS Publications
A novel approach has been developed to prepare polyethylenimine functionalized hybrid
silica spheres with a diameter of∼ 10 nm, which show excellent delivery efficiency of siRNA …