Highlights•Artificial enzymes can be designed through supramolecular interactions.•The
method of designing artificial enzymes without precise design based on protein complexes …

How the three-dimensional (3D) chiral environment affects the biocatalysis remains an
important issue, thereby inspiring the development of a microenvironment that highly mimics …

The advent of biotechnology has enabled metabolic engineers to assemble heterologous
pathways in cells to produce a variety of products of industrial relevance, often in a …

Enzymatic catalytic processes possess great potential in chemical manufacturing, including
pharmaceuticals, fuel production and food processing. However, the engineering of …

Enzyme compartmentalization is one of the main strategies exploited by nature to create
physically separated chemical environments that allow simultaneous enzyme reactions …

Metalloenzymes play essential roles in biology, whereas artificial metalloenzymes use
synthetic metal cofactors for promoting non-natural reactions. In the past decades …

Natural enzymes are crucial catalysts that not only control over the biotransformation in
intracellular environments with high efficiency but also are widely harnessed in vitro for …

Interest in well-defined surface architectures has shown a steady increase, particularly
among those involved in biological applications where the reactivity of functional groups on …

The rapid growth in nanotechnology and biotechnology offers a wealth of opportunities for
the combination of natural enzymes with different kinds of nanomaterial. Here, we highlight …

Functional nanomaterials have found wide applications in diverse areas because of their
intrinsically different properties compared to their bulk counterparts. To achieve the goal of …