Primary electrical heart diseases, often considered channelopathies, are inherited genetic
abnormalities of cardiomyocyte electrical behavior carrying the risk of malignant arrhythmias …

Purely electrical heart diseases, defined by the absence of any structural cardiac defects,
are responsible for a large number of sudden, unexpected deaths in otherwise healthy …

Sudden cardiac death occurs in a minority of patients in the absence of structural or
functional abnormalities. In this category, pure electrical heart diseases are responsible for a …

Primary electrical diseases or channelopathies are inherited genetic alterations of the cell
ionic and electrical behavior leading to various cardiac arrhythmias carrying the risk of …

Forty per cent (40%) of sudden unexpected natural deaths in people under 35 years of age
are associated with a negative autopsy, and the cardiac ion channelopathies are the prime …

Advanced progress in genetics and molecular biology has rendered it possible to define a
series of inherited arrhythmogenic disorders linked to sudden cardiac death (SCD) in young …

The cardiac channelopathies are a group of diseases with (disease-) specific
electrocardiographic (ECG) characteristics and a disease-specific risk of sudden cardiac …

Sudden cardiac death, secondary to malignant ventricular arrhythmias, has traditionally
been associated with structural heart disease. An important exception includes a group of …

Long QT syndrome, short QT syndrome, Brugada syndrome and catecholaminergic
polymorphic ventricular tachycardia are inherited primary electrical disorders that …

Sudden cardiac death poses a unique challenge to clinicians because it may be the only
symptom of an inherited heart condition. Indeed, inherited heart diseases can cause sudden …