Capsazepine activates amiloride-insensitive ENaC-like channels in human leukemia cells

DV Lysikova, VY Vasileva… - Biochemical and …, 2023 - Elsevier
Sodium influx carried out by ion channels is one of the main regulators of water-salt and
volume balance in cells of blood origin. Previously, we described amiloride-insensitive …

Extracellular protease trypsin activates amiloride‐insensitive sodium channels in human leukemia cells

AV Sudarikova, VY Vasileva… - Journal of Cellular …, 2019 - Wiley Online Library
Sodium influx is tightly regulated in the cells of blood origin. Amiloride‐insensitive sodium
channels were identified as one of the main sodium‐transporting pathways in leukemia …

Molecular and functional identification of sodium channels in K562 cells

AV Sudarikova, IO Vassilieva, EA Morachevskaya… - Cell and Tissue …, 2012 - Springer
Modulations of ion channel activity underlie rapid changes in membrane transport of cations
in various nonexcitable cells. Previously, in smooth muscle cells, macrophages …

Amiloride-insensitive sodium channels are directly regulated by actin cytoskeleton dynamics in human lymphoma cells

AV Sudarikova, OA Tsaplina… - Biochemical and …, 2015 - Elsevier
Sodium influx mediated by ion channels of plasma membrane underlies fundamental
physiological processes in cells of blood origin. However, little is known about the single …

Functional properties and cytoskeletal-dependent regulation of sodium channels in leukemia cell membranes

EA Vedernikova, AV Maksimov, N IuA - Tsitologiia, 1997 - europepmc.org
The paper is devoted to membrane mechanisms of sodium influx from the extracellular
medium to the cytoplasm in nonexcitable cells. With the use of patch clamp technique, the …

A cell shrinkage‐induced non‐selective cation conductance with a novel pharmacology in Ehrlich–Lettre‐ascites tumour cells

P Lawonn, EK Hoffmann, C Hougaard, F Wehner - FEBS letters, 2003 - Wiley Online Library
In whole‐cell recordings on Ehrlich–Lettre‐ascites tumour (ELA) cells, the shrinkage‐
induced activation of a cation conductance with a selectivity ratio P Na: P Li: PK: P choline: P …

Icilin activates the δ-subunit of the human epithelial Na+ channel

H Yamamura, S Ugawa, T Ueda, M Nagao… - Molecular …, 2005 - ASPET
The amiloride-sensitive epithelial Na+ channel (ENaC) regulates Na+ homeostasis in cells
and across epithelia. Four homologous ENaC subunits (α, β, γ, and δ) have been isolated in …

[HTML][HTML] Steroids and exogenous γ-ENaC subunit modulate cation channels formed by α-ENaC in human B lymphocytes

HP Ma, O Al-Khalili, S Ramosevac, S Saxena… - Journal of Biological …, 2004 - ASBMB
Previous studies using whole-cell recording methods suggest that human B lymphocytes
express an amiloride-sensitive, sodium-permeable channel. The present studies aim to …

[HTML][HTML] Ca-dependent regulation of Na+-selective channels via actin cytoskeleton modification in leukemia cells

AV Maximov, EA Vedernikova, H Hinssen, SY Khaitlina… - FEBS letters, 1997 - Elsevier
With the use of the patch-clamp technique, physiological mechanisms of Na+ channel
regulation involving submembranous actin rearrangements were examined in human …

Voltage-dependent conductance changes in a nonvoltage-activated sodium current from a mast cell line

AB Parekh - The Journal of membrane biology, 1998 - Springer
Nonexcitable cells do not express voltage-activated Na+ channels. Instead, selective Na+
influx is accomplished through GTP-activated Na+ channels, the best characterized of which …