The predictive significance of the Advanced Lung Cancer Inflammation Index (ALI) in patients with melanoma treated with immunotherapy as second-line therapy

X Cheng, Y Dong, F Lou - Cancer Management and Research, 2021 - Taylor & Francis
Purpose The advanced lung cancer inflammation index (ALI) is a useful tool to predict the
clinical outcome in several malignancies. The ALI not only contains indices related to …

Prognostic utility of baseline neutrophil-to-lymphocyte ratio in patients receiving immune checkpoint inhibitors: a review and meta-analysis

DB Sacdalan, JA Lucero, DL Sacdalan - OncoTargets and therapy, 2018 - Taylor & Francis
Introduction Systemic inflammation is associated with prognosis in solid tumors. The
neutrophil-to-lymphocyte ratio (NLR) is a marker for the general immune response to various …

Development of lymphopenia during therapy with immune checkpoint inhibitors is associated with poor outcome in metastatic cutaneous melanoma

D Tomsitz, M Schlaak, S Zierold, G Pesch, TU Schulz… - Cancers, 2022 - mdpi.com
Simple Summary Predictive markers are necessary for immune checkpoint inhibitor (ICI)
therapy. The aim of our retrospective study was to investigate the relationship between the …

[HTML][HTML] Systemic immune-inflammation index and circulating T-cell immune index predict outcomes in high-risk acral melanoma patients treated with high-dose …

J Yu, X Wu, H Yu, S Li, LL Mao, Z Chi, L Si… - Translational …, 2017 - Elsevier
High-dose interferon alfa-2b (IFN-α-2b) improves the survival of patients with high-risk
melanoma. We aimed to identify baseline peripheral blood biomarkers to predict the …

[HTML][HTML] Mortality in cutaneous malignant melanoma and its association with Neutrophil-to-Lymphocyte ratio.

ME Pinto-Paz, JM Cotrina-Concha… - Cancer Treatment and …, 2021 - Elsevier
Introduction Cutaneous malignant melanoma (CMM) incidence has risen rapidly in the last
50 years. Poor progression and high mortality characterize CMM, making a thorough …

[HTML][HTML] Back to simplicity: a four-marker blood cell score to quantify prognostically relevant myeloid cells in melanoma patients

V Huber, L Di Guardo, L Lalli, D Giardiello… - … for ImmunoTherapy of …, 2021 - ncbi.nlm.nih.gov
Background Myeloid-derived suppressor cells (MDSC), a cornerstone of cancer-related
immunosuppression, influence response to therapy and disease outcomes in melanoma …

The derived neutrophil-to-lymphocyte ratio is an independent prognostic factor in transplantation ineligible patients with multiple myeloma

GW Lee, SW Park, SI Go, HG Kim, MK Kim, CK Min… - Acta …, 2018 - karger.com
Background: The neutrophil-to-lymphocyte ratio (NLR) is an independent prognostic marker
in solid and hematological cancers. While the derived NLR (dNLR) was shown to be non …

The neutrophil–lymphocyte ratio and its utilisation for the management of cancer patients in early clinical trials

R Kumar, E Geuna, V Michalarea… - British journal of …, 2015 - nature.com
Background: Inflammation is critical to the pathogenesis and progression of cancer, with a
high neutrophil–lymphocyte ratio (NLR) associated with poor prognosis. The utility of …

Neutrophil‐to‐lymphocyte ratio in head and neck cancer prognosis: a systematic review and meta‐analysis

MA Mascarella, E Mannard, SD Silva, A Zeitouni - Head & neck, 2018 - Wiley Online Library
Background Hematologic markers, such as the neutrophil‐to‐lymphocyte ratio (NLR),
characterize the inflammatory response to cancer and are associated with poorer survival in …

Effect of the lymphocyte-to-monocyte ratio on the clinical outcome of chemotherapy administration in advanced melanoma patients

AA Leontovich, RS Dronca, WK Nevala… - Melanoma …, 2017 - journals.lww.com
Skin cancer affects more individuals in the USA than any other malignancy and malignant
melanoma is particularly deadly because of its metastatic potential. Melanoma has been …