Staphylococcus aureus is a leading cause of significant morbidity and mortality and an
enormous economic burden to public health worldwide. Infections caused by methicillin …

Staphylococcus aureus is the leading cause of skin and soft tissue infections (SSTIs) in the
US as well as more serious invasive diseases, including bacteremia, sepsis, endocarditis …

Staphylococcus aureus causes a wide range of diseases from skin infections to life
threatening invasive diseases such as bacteremia, endocarditis, pneumonia, surgical site …

Staphylococcus aureus has been acquiring multiple drug resistance and has evolved into
superbugs such as Methicillin/Vancomycin-resistant S. aureus (MRSA/VRSA) and …

Bacterial vaccines have made dramatic impacts upon morbidity and mortality caused by a
number of common pathogens, but a vaccine to prevent Staphylococcus aureus infections …

We assessed the safety, reactogenicity and immunogenicity of a staphylococcal vaccine
combining capsular polysaccharides types 5 and 8 (CPS5/8), conjugated to tetanus toxoid …

Staphylococcus aureus infections are a major public health issue, and a vaccine is urgently
needed. Despite a considerable promise in preclinical models, all vaccines tested thus far …

Abstract Treatment of Staphylococcus aureus infections has become complicated owing to
growing antibiotic resistance mechanisms and due to the multitude of virulence factors …

In the Gram-positive pathogen Staphylococcus aureus, pore-forming toxins (PFTs), such as
leukocidins and hemolysins, play prominent roles in staphylococcal pathogenesis by killing …

Staphylococcus aureus causes significant illnesses throughout the world, including toxic
shock syndrome (TSS), pneumonia, and infective endocarditis. Major contributors to S …