Influence of dendrimer surface charge on the bioactivity of 2-methoxyestradiol complexed with dendrimers

X Shi, I Lee, X Chen, M Shen, S Xiao, M Zhu, JR Baker… - Soft Matter, 2010 - pubs.rsc.org
We report the complexation of a potential anticancer agent 2-methoxyestradiol (2-ME) with
generation 5 (G5) poly (amidoamine) dendrimers having different surface functional groups …

Encapsulation of 2-methoxyestradiol within multifunctional poly (amidoamine) dendrimers for targeted cancer therapy

Y Wang, R Guo, X Cao, M Shen, X Shi - Biomaterials, 2011 - Elsevier
We report here a general approach to using multifunctional poly (amidoamine)(PAMAM)
dendrimer-based platform to encapsulate a potential anticancer drug for targeted cancer …

Dendrimers in anticancer drug delivery: mechanism of interaction of drug and dendrimers

J Singh, K Jain, NK Mehra, NK Jain - Artificial cells, nanomedicine …, 2016 - Taylor & Francis
Dendrimers represents a novel class of macromolecules, which are derived from branches
upon branches type structural design. Dendrimers are emerging as promising drug-delivery …

Impact of dendrimer surface functional groups on the release of doxorubicin from dendrimer carriers

M Zhang, R Guo, M Keri, I Banyai… - The Journal of …, 2014 - ACS Publications
Generation 5 (G5) poly (amidoamine) dendrimers with acetyl (G5. NHAc), glycidol hydroxyl
(G5. NGlyOH), and succinamic acid (G5. SAH) terminal groups were used to physically …

Atomic level insights into realistic molecular models of dendrimer-drug complexes through MD simulations

V Jain, PK Maiti, PV Bharatam - The Journal of Chemical Physics, 2016 - pubs.aip.org
Computational studies performed on dendrimer-drug complexes usually consider 1: 1
stoichiometry, which is far from reality, since in experiments more number of drug molecules …

Dendrimers for drug delivery

AM Caminade, CO Turrin - Journal of Materials Chemistry B, 2014 - pubs.rsc.org
Due to their nanometric size, dendrimers have been considered as potentially suitable as
new vehicles for drug delivery since their infancy. The association of a dendrimer and a drug …

Understanding the pharmaceutical aspects of dendrimers for the delivery of anticancer drugs

SK Dubey, S Salunkhe, M Agrawal, M Kali… - Current Drug …, 2020 - ingentaconnect.com
Dendrimers are emerging class of nanoparticles used in targeted drug delivery systems.
These are radially symmetric molecules with well-defined, homogeneous, and …

[HTML][HTML] Dendrimers bind antioxidant polyphenols and cisplatin drug

A Abderrezak, P Bourassa, JS Mandeville… - PloS one, 2012 - journals.plos.org
Synthetic polymers of a specific shape and size play major role in drug delivery systems.
Dendrimers are unique synthetic macromolecules of nanometer dimensions with a highly …

Host− guest chemistry of dendrimer− drug complexes. 6. Fully acetylated dendrimers as biocompatible drug vehicles using dexamethasone 21-phosphate as a model …

K Yang, L Weng, Y Cheng, H Zhang… - The Journal of …, 2011 - ACS Publications
Fully acetylated poly (amidoamine)(PAMAM) dendrimer was proposed as a biocompatible
drug vehicle using dexamethasone 21-phosphate (Dp21) as a model drug. NMR techniques …

Recent advances in dendrimer-based nanoplatform for cancer treatment: A review

RS Ambekar, M Choudhary… - European polymer …, 2020 - Elsevier
Out of the total deaths, 70% death occurs in middle and low-income countries due to cancer
and according to world cancer report 2014, total annual economic cost of cancer in 2010 …