Application of deep learning on single-cell RNA sequencing data analysis: a review

M Brendel, C Su, Z Bai, H Zhang… - Genomics …, 2022 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has become a routinely used technique to
quantify the gene expression profile of thousands of single cells simultaneously. Analysis of …

Deep learning-based advances and applications for single-cell RNA-sequencing data analysis

S Bao, K Li, C Yan, Z Zhang, J Qu… - Briefings in …, 2022 - academic.oup.com
The rapid development of single-cell RNA-sequencing (scRNA-seq) technology has raised
significant computational and analytical challenges. The application of deep learning to …

Single-cell RNA sequencing analysis: a step-by-step overview

S Slovin, A Carissimo, F Panariello, A Grimaldi… - RNA bioinformatics, 2021 - Springer
Thanks to innovative sample-preparation and sequencing technologies, gene expression in
individual cells can now be measured for thousands of cells in a single experiment. Since its …

Deep learning tackles single-cell analysis—a survey of deep learning for scRNA-seq analysis

M Flores, Z Liu, T Zhang, MM Hasib… - Briefings in …, 2022 - academic.oup.com
Since its selection as the method of the year in 2013, single-cell technologies have become
mature enough to provide answers to complex research questions. With the growth of single …

SingleCAnalyzer: interactive analysis of single cell RNA-Seq data on the cloud

C Prieto, D Barrios, A Villaverde - Frontiers in bioinformatics, 2022 - frontiersin.org
Single-cell RNA sequencing (scRNA-Seq) enables researchers to quantify the
transcriptomes of individual cells. The capacity of researchers to perform this type of analysis …

Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications

M Su, T Pan, QZ Chen, WW Zhou, Y Gong, G Xu… - Military Medical …, 2022 - Springer
The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has
advanced our understanding of the pathogenesis of disease and provided valuable insights …

Single-cell RNA-seq technologies and related computational data analysis

G Chen, B Ning, T Shi - Frontiers in genetics, 2019 - frontiersin.org
Single-cell RNA sequencing (scRNA-seq) technologies allow the dissection of gene
expression at single-cell resolution, which greatly revolutionizes transcriptomic studies. A …

A comprehensive survey of statistical approaches for differential expression analysis in single-cell RNA sequencing studies

S Das, A Rai, ML Merchant, MC Cave, SN Rai - Genes, 2021 - mdpi.com
Single-cell RNA-sequencing (scRNA-seq) is a recent high-throughput sequencing
technique for studying gene expressions at the cell level. Differential Expression (DE) …

Exploring the single-cell RNA-seq analysis landscape with the scRNA-tools database

L Zappia, B Phipson, A Oshlack - PLoS computational biology, 2018 - journals.plos.org
As single-cell RNA-sequencing (scRNA-seq) datasets have become more widespread the
number of tools designed to analyse these data has dramatically increased. Navigating the …

scAAGA: Single cell data analysis framework using asymmetric autoencoder with gene attention

R Meng, S Yin, J Sun, H Hu, Q Zhao - Computers in biology and medicine, 2023 - Elsevier
In recent years, single-cell RNA sequencing (scRNA-seq) has emerged as a powerful
technique for investigating cellular heterogeneity and structure. However, analyzing scRNA …