The trans isomer of cisplatin, transplatin, is an inactive platinum drug; however, a number of
analogues, such as trans complexes with iminoether, thiazole and isopropylamine ligands …

Both trans-and cis-PtCl 2 (NH 3)(L) compounds have been synthesized, L representing
either the imino ether HN= C (OMe) Me having a Z or E configuration at the C= N double …

Imino ligands have proven to be able to activate the trans geometry of platinum (II)
complexes towards antitumor activity. These ligands, like aromatic N-donor heterocycles …

A series of iminopyridine complexes of platinum (II), bearing a flexible diethereal, aryl
terminated residue, where the size of aryl group is varied from phenyl to 9-anthracenyl, was …

The reactions of the nitrile complexes cis-and trans-[PtCl2 (NCR) 2](R= Me, Et, CH2Ph, Ph)
with an excess of ethanethiol, EtSH, in the presence of a catalytic amount of n-BuLi in …

Starting from the pioneering discovery of picoplatin and phenanthriplatin, many efforts were
realized by different research groups in the synthesis of different platinum (II) complexes …

In the late eighties, Farrell and co-workers developed the so called nonclassical platinum
drugs, which are multinuclear and therefore offer a completely different binding mechanism …

The success of cis-dichlorodiammineplatinum (Il)(cisplatin) as an anticancer drug has
prompted research on a broad spectrum of new platinum complexes which also show …

Cisplatin-type derivatives cis-bis (cyclopentylamine) bis (alkoxyacetato-κO) platinum
(II)(alkoxyacetate= ethoxyacetate, isopropoxyacetate and tert-butoxyacetate)(1–3) have …

“Non-classical” di-and trinuclear Pt (II) complexes with polydentate nitrogen ligands; ionic
[(PtCl2) 2 (tptz) 2 (μ-PtClNCPh)] Cl (1)[tptz= 2, 4, 6-tris (2-pyridyl)-1, 3, 5-triazine],[(PtCl2) 2 …