Numerous therapeutic strategies have been described for prevention and reduction of
hypertrophic scars and keloids, but none of the treatments is effective in all patients. No …

Background: In 2010, this Journal published my comprehensive review of the literature on
hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the …

Hypertrophic scars and keloids are caused by excessive tissue response to dermal injury
due to local fibroblast proliferation and collagen overproduction. This response occurs …

Keloids and hypertrophic scars are benign fibrous overgrowths of scar tissue, which results
from an abnormal response to trauma. Several therapeutic modalities have been described …

Hypertrophic scars and keloids can have significant detrimental effects on patients both
psychosocially and functionally. A careful identification of patient risk factors and a …

Keloids and hypertrophic scars occur anywhere from 30 to 90% of patients, and are
characterized by pathologically excessive dermal fibrosis and aberrant wound healing. Both …

Background: There is no uniform treatment for pathological scars, including keloids and
hypertrophic scars, in clinic currently. Previously, multiple randomized controlled trials have …

Scars vary from mature linear scars to abnormal excessive scars such as hypertrophic scars
and keloid scars. Keloid scars are fibro-proliferative disease entities that reflect an abnormal …

BACKGROUND Keloid and hypertrophic scars represent an aberrant response to the wound
healing process. These scars are characterized by dysregulated growth with excessive …

Hypertrophic scars, resulting from alterations in the normal processes of cutaneous wound
healing, are characterized by proliferation of dermal tissue with excessive deposition of …