[HTML][HTML] Enhancing Photodynamic Therapy Efficacy Through Silica Nanoparticle-Mediated Delivery of Temoporfin for Targeted Breast Cancer Treatment

GN Makhadmeh, T AlZoubi, AM Aljarrah… - Photodiagnosis and …, 2024 - Elsevier
Photodynamic therapy (PDT), a novel approach to cancer treatment, relies fundamentally on
two key elements: a light source and a photosensitizing agent. A primary challenge in PDT is …

Silica-based nanoparticles are efficient delivery systems for temoporfin

I Brezániová, K Záruba, J Králová, A Sinica… - Photodiagnosis and …, 2018 - Elsevier
Background Drug targeting using functionalized nanoparticles to advance their transport to
the dedicated site became a new standard in novel anticancer methods Anticancer …

Current state of the nanoscale delivery systems for temoporfin-based photodynamic therapy: Advanced delivery strategies

I Yakavets, M Millard, V Zorin, HP Lassalle… - Journal of controlled …, 2019 - Elsevier
Enthusiasm for photodynamic therapy (PDT) as a promising technique to eradicate various
cancers has increased exponentially in recent decades. The majority of clinically approved …

Mesoporous silica-based nanoplatforms for the delivery of photodynamic therapy agents

S Hong, Y Choi - Journal of pharmaceutical investigation, 2018 - Springer
Photodynamic therapy (PDT) is an established method for the treatment of cancer which
utilizes light, a photosensitizer (PS), and oxygen. Unfavourable characteristics of most PSs …

[HTML][HTML] Verteporfin based silica nanoparticle for in vitro selective inhibition of human highly invasive melanoma cell proliferation

M Rizzi, S Tonello, BM Estevão, E Gianotti… - … of Photochemistry and …, 2017 - Elsevier
Photodinamic therapy (PDT) has gained an increasing interest as a new tool to treat skin
cancers such as melanoma. This clinical approach take advantage from the combination of …

Recent Innovations of Mesoporous Silica Nanoparticles Combined with Photodynamic Therapy for Improving Cancer Treatment

DS Nady, A Hassan, MU Amin, U Bakowsky, SA Fahmy - Pharmaceutics, 2023 - mdpi.com
Cancer is a global health burden and is one of the leading causes of death. Photodynamic
therapy (PDT) is considered an alternative approach to conventional cancer treatment. PDT …

Biological evaluation of photodynamic effect mediated by nanoparticles with embedded porphyrin photosensitizer

L Žárská, Z Malá, K Langová, L Malina… - International Journal of …, 2022 - mdpi.com
Clinically approved photodynamic therapy (PDT) is a minimally invasive treatment
procedure that uses three key components: photosensitization, a light source, and tissue …

Photosensitizer‐Mesoporous Silica Nanoparticles Combination for Enhanced Photodynamic Therapy

R Prieto‐Montero, T Arbeloa… - Photochemistry and …, 2023 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) are widely known for their versatile applications.
One of the most extended is as drug delivery systems for the treatment of cancer and other …

[HTML][HTML] Verteporfin-loaded mesoporous silica nanoparticles inhibit mouse melanoma proliferation in vitro and in vivo

N Clemente, I Miletto, E Gianotti, M Invernizzi… - … of Photochemistry and …, 2019 - Elsevier
Melanoma is one of the most lethal tumors among the skin cancers, arising from complex
genetic mutations in melanocyte. Melanoma microenvironment is very heterogeneous …

Advancing Photodynamic Therapy Efficiency on MCF-7 Breast Cancer Cells through Silica Nanoparticles-Safranin Encapsulation: In-Vitro Evaluation

K Aljarrah, MAH Al-Akhras, GN Makhadmeh… - Journal of Composites …, 2023 - mdpi.com
Efficient drug delivery to target tissue is a major challenge in many cancer treatment
modalities. Silica nanoparticles (SiNPs) have been identified as an ideal drug carrier due to …