Diatom-derived mesoporous silica nanoparticles loaded with fucoidan for enhanced chemo-photodynamic therapy

MH Tsou, ZY Wu, G Chen, CC Lee, ZH Lee… - International Journal of …, 2023 - Elsevier
Combination therapy merges chemical photodynamic therapy (CPDT) to improve cancer
treatment. It synergizes chemotherapy with photodynamic therapy (PDT), using …

Biolistic Delivery of Photosensitizer‐Loaded Porous Si Carriers for Localized Photodynamic Therapy

E Haimov‐Talmoud, M Rosenberg… - Advanced Materials …, 2023 - Wiley Online Library
Among numerous approaches for treating cancer, clinically approved photodynamic therapy
(PDT) is considered a promising non‐invasive therapeutic strategy for solid tumors. While …

Photodynamic application of protoporphyrin IX as a photosensitizer encapsulated by silica nanoparticles

GN Makhadmeh, A Abdul Aziz - Artificial cells, nanomedicine, and …, 2018 - Taylor & Francis
Abstract Background Achieved Silica Nanoparticles (SiNPs) to encapsulate the
photosensitizer [Protoporphyrin IX (PpIX)] in photodynamic therapy (PDT) application was …

[HTML][HTML] Targeted and effective photodynamic therapy for cancer using functionalized nanomaterials

EJ Hong, DG Choi, MS Shim - Acta Pharmaceutica Sinica B, 2016 - Elsevier
Photodynamic therapy (PDT) is an emerging, non-invasive therapeutic strategy that involves
photosensitizer (PS) drugs and external light for the treatment of diseases. Despite the great …

Silk sericin-based nanoparticle as the photosensitizer chlorin e6 carrier for enhanced cancer photodynamic therapy

YE Gao, S Hou, J Cheng, X Li, Y Wu… - ACS Sustainable …, 2021 - ACS Publications
With the merits of noninvasiveness, flexibility of treatment, and nonsystemic toxicity,
photodynamic therapy (PDT) holds great promise in fighting against malignant cancers …

Curcumin-loaded PEGylated mesoporous silica nanoparticles for effective photodynamic therapy

G Kuang, Q Zhang, S He, Y Liu - RSC advances, 2020 - pubs.rsc.org
Curcumin (Cur) can be used as a photosensitizer in the photodynamic therapy (PDT) of
cancer, but its low bioavailability limits further clinical application. A mesoporous silica …

Recent Advancements in Nanomaterials for Photodynamic Therapy of Cancers

AM Shabbirahmed, M Kumaravel, P Somu… - Handbook of Oxidative …, 2022 - Springer
Surgery, chemotherapy, and radiotherapy are the commonly used therapeutic interventions
for cancerous tumors but they often cause deleterious side effects to the normal cells …

Advances in nanomaterials for photodynamic therapy applications: Status and challenges

J Chen, T Fan, Z Xie, Q Zeng, P Xue, T Zheng, Y Chen… - Biomaterials, 2020 - Elsevier
Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to
radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although …

Verteporfin-Loaded Mesoporous Silica Nanoparticles' Topical Applications Inhibit Mouse Melanoma Lymphangiogenesis and Micrometastasis In Vivo

N Clemente, I Miletto, E Gianotti, M Sabbatini… - International Journal of …, 2021 - mdpi.com
Photodynamic therapy (PDT) has been pointed out as a candidate for improving melanoma
treatment. Nanotechnology application in PDT has increased its efficacy by reducing side …

Encapsulation of glycosylated porphyrins in silica nanoparticles to enhance the efficacy of cancer photodynamic therapy

W Borzęcka, PMR Pereira, R Fernandes… - Materials …, 2021 - pubs.rsc.org
In this study, we encapsulated S-galactosylated and S-glucosylated porphyrins (Pors) into
amorphous silica nanoparticles (SNPs) to enhance the photodynamic therapy (PDT) activity …