The mismatch repair system (mutS and mutL) in Acinetobacter baylyi ADP1

H Zhou, L Zhang, Q Xu, L Zhang, Y Yu, X Hua - BMC microbiology, 2020 - Springer
Background Acinetobacter baylyi ADP1 is an ideal bacterial strain for high-throughput
genetic analysis as the bacterium is naturally transformable. Thus, ADP1 can be used to …

Functions of the Mismatch Repair GenemutS from Acinetobacter sp. Strain ADP1

DM Young, LN Ornston - Journal of Bacteriology, 2001 - Am Soc Microbiol
The genus Acinetobacter encompasses a heterogeneous group of bacteria that are
ubiquitous in the natural environment due in part to their ability to adapt genetically to novel …

Reduced mutation rate and increased transformability of transposon-free Acinetobacter baylyi ADP1-ISx

GA Suárez, BA Renda, A Dasgupta… - Applied and …, 2017 - Am Soc Microbiol
The genomes of most bacteria contain mobile DNA elements that can contribute to
undesirable genetic instability in engineered cells. In particular, transposable insertion …

Natural transformation as a tool in Acinetobacter baylyi: Evolution by amplification of gene copy number

I Pardo, SR Bedore, MP Tumen-Velasquez… - Methods in …, 2023 - Elsevier
For many years, the natural competency of Acinetobacter baylyi ADP1 facilitated studies of
bacterial metabolism, biochemistry, and physiology. With the advent of synthetic biology …

Genome instability mediates the loss of key traits by Acinetobacter baylyi ADP1 during laboratory evolution

BA Renda, A Dasgupta, D Leon… - Journal of bacteriology, 2015 - Am Soc Microbiol
Acinetobacter baylyi ADP1 has the potential to be a versatile bacterial host for synthetic
biology because it is naturally transformable. To examine the genetic reliability of this …

Characterization of the DNA mismatch repair proteins MutS and MutL in a hypermutator Acinetobacter baumannii

B Deihim, M Hassanzadeh, NZ Shafiei-Jandaghi… - Microbial …, 2017 - Elsevier
Mutations of mutS and mutL genes have been linked with the emergence of hypermutator
(HPM) phenotype in several bacteria. Nevertheless, there is scarce evidence that these …

Deletion Mutations Caused by DNA Strand Slippage in Acinetobacter baylyi

JM Gore, FA Ran, LN Ornston - Applied and environmental …, 2006 - Am Soc Microbiol
Short nucleotide sequence repetitions in DNA can provide selective benefits and also can
be a source of genetic instability arising from deletions guided by pairing between …

Genome‐wide selection for increased copy number in Acinetobacter baylyi ADP1: locus and context‐dependent variation in gene amplification

SC Seaton, KT Elliott, LE Cuff… - Molecular …, 2012 - Wiley Online Library
Renewed interest in gene amplification stems from its importance in evolution and a variety
of medical problems ranging from drug resistance to cancer. However, amplified DNA …

Analysis of IS1236-Mediated Gene Amplification Events in Acinetobacter baylyi ADP1

LE Cuff, KT Elliott, SC Seaton, MK Ishaq… - Journal of …, 2012 - Am Soc Microbiol
Recombination between insertion sequence copies can cause genetic deletion, inversion,
or duplication. However, it is difficult to assess the fraction of all genomic rearrangements …

Diverse responses to UV light exposure in Acinetobacter include the capacity for DNA damage-induced mutagenesis in the opportunistic pathogens Acinetobacter baumannii …

JM Hare, JA Bradley, C Lin, TJ Elam - Microbiology, 2012 - microbiologyresearch.org
Error-prone and error-free DNA damage repair responses that are induced in most bacteria
after exposure to various chemicals, antibiotics or radiation sources were surveyed across …