Long non‑coding RNAs as potential therapeutic targets in non‑small cell lung cancer

P Tang, D Sun, W Xu, H Li… - … Journal of Molecular …, 2023 - spandidos-publications.com
Non‑small cell lung cancer (NSCLC) is one of the most common malignancies with a high
morbidity and mortality rate. Long non‑coding RNAs (lncRNAs) have been reported to be …

[HTML][HTML] Long non-coding RNA as potential biomarkers in non-small-cell lung cancer: What do we know so far?

MA Osielska, PP Jagodziński - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Non-small-cell lung cancer (NSCLC) remains one of the most frequent types of lung cancer
characterized by its local advancement at diagnosis. Therefore, identification of new …

Long non‑coding RNAs: Novel links in respiratory diseases

Y Liu, R Zhang, K Ying - Molecular medicine reports, 2015 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) represent a surprisingly novel field in mammalian
transcriptome research. With the development of RNA sequencing technology and …

[HTML][HTML] Non-coding RNAs in lung cancer

B Ricciuti, C Mecca, L Crinò, S Baglivo, M Cenci… - …, 2014 - ncbi.nlm.nih.gov
The discovery that protein-coding genes represent less than 2% of all human genome, and
the evidence that more than 90% of it is actively transcribed, changed the classical point of …

Non-coding RNAs in lung tumor initiation and progression

RM Santos, C Moreno, WC Zhang - International Journal of Molecular …, 2020 - mdpi.com
Lung cancer is one of the deadliest forms of cancer affecting society today. Non-coding
RNAs, such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs …

LncRNA in tumorigenesis of non-small-cell lung cancer: From bench to bedside

Q Hu, H Ma, H Chen, Z Zhang, Q Xue - Cell death discovery, 2022 - nature.com
Lung cancer has been one of the leading causes of cancer-related death worldwide, and
non-small-cell lung cancer (NSCLC) accounts for the majority of lung cancer morbidity, yet …

Major tumor suppressor and oncogenic non-coding RNAs: clinical relevance in lung cancer

K Inamura - Cells, 2017 - mdpi.com
Lung cancer is the leading cause of cancer deaths worldwide, yet there remains a lack of
specific and sensitive tools for early diagnosis and targeted therapies. High-throughput …

[HTML][HTML] Intersecting transcriptomic profiling technologies and long non-coding RNA function in lung adenocarcinoma: discovery, mechanisms, and therapeutic …

J Castillo, TR Stueve, CN Marconett - Oncotarget, 2017 - ncbi.nlm.nih.gov
Previously thought of as junk transcripts and pseudogene remnants, long non-coding RNAs
(lncRNAs) have come into their own over the last decade as an essential component of …

[HTML][HTML] Competing endogenous RNAs in lung cancer

M Zhao, J Feng, L Tang - Cancer biology & medicine, 2021 - ncbi.nlm.nih.gov
Competing endogenous RNAs (ceRNAs) containing microRNA response elements can
competitively interact with microRNA via miRNA response elements, which can combine …

Diagnostic and prognostic potential of circulating long non-coding RNAs in non small cell lung cancer

W Peng, J Wang, B Shan, Z Peng, Y Dong… - Cellular Physiology and …, 2018 - karger.com
Lung cancer is the leading cause of cancer-related mortality worldwide. Approximately 80%
of lung cancer cases are non–small cell lung carcinoma (NSCLC). However current …